nicotinamide adenine dinucleotide
A compound in every cell, needed to make energy. Clinics offer it as drips and injections. No such medicine in the EU or US.
This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.
Doping. The substance is not on the WADA list, but drips and injections above 100 mL in 12 hours are banned, except in hospital care and medical tests.
Safety. A 2026 review of NAD+ drips found few data in people: small studies without comparison groups, observations and case reports. Sources: study 1, study 2.
Risk of fakes. We found no tests of products sold outside pharmacies.
| Where | Status | Checked | |
|---|---|---|---|
| PL | No approval | The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. This covers medicines, not supplements. Source | Not yet |
| EU | No approval | The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). This covers medicines, not supplements. Source | Not yet |
| US | No approval | The FDA drug register has no such medicine. Source | Not yet |
Scientific papers per year 2015–2025
These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.
Not clear. A 2026 review found no study of the effects of NAD+ itself given by drip or injection. Studies test NMN and NR, which the body turns into NAD+, and their results on health are mixed or show no effect.
What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.
FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.
A fertility doctor covers NAD+ drips marketed for fertility. She says the excitement rests mainly on animal studies, human data are thin and not peer-reviewed, and recalls a young woman who died after such a drip at a med spa.
A short video in which the author rates popular peptides on a scale from S to F. His ratings are an opinion on whether something is worth taking. Our grades from A to E only say how strong the studies are. The comparison below is based on the video description.
| Studies | Kind of study | Who was studied | People | Duration | Dose as studied | Who paid |
|---|---|---|---|---|---|---|
| NAD⁺ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence. | Review of studies | Human and rodent studies of NAD-related compounds | – | – | – | Unknown |
We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.
