ligandrol · VK5211
A SARM still being studied. No such medicine exists, and the Polish sanitary inspectorate lists it as not allowed in supplements.
This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.
Safety. Two case reports describe severe liver damage with blocked bile flow, confirmed by biopsy. Sources: study 1, study 2.
Risk of fakes. Of 44 products sold as SARMs, 52% held any SARM and 41% matched the label. In Italy, products held 30% to 90% of the amount claimed. Sources: study 1, study 2.
| Where | Status | Checked | |
|---|---|---|---|
| PL | No approval | No approval found. The Polish sanitary inspectorate lists SARMs as not allowed in food supplements. Source | Not yet |
| EU | No approval | The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). Source | Not yet |
| US | No approval | The FDA drug register has no such medicine. Source | Not yet |
Scientific papers per year 2015–2025
These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.
Effect in studies. One 21-day study of 76 healthy men. Body mass without fat rose and fat did not change. We found nothing longer.
What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.
| Most often reported | Reports |
|---|---|
| Red blood cells destroyed in the cold | 2 |
| Seizure | 2 |
| Blocked bile flow | 1 |
| Epstein-Barr virus infection | 1 |
| Red blood cells destroyed | 1 |
| Liver failure | 1 |
| Sudden liver inflammation | 1 |
| Liver inflammation with blocked bile flow | 1 |
Serious means the person went to hospital, their life was in danger, they were left with lasting harm, or they died. One report can list several side effects.
FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.
A urologist who works on men's health goes through the studies on popular SARMs, MK-677 and cardarine: muscle gain, lower testosterone, the liver, cholesterol, fertility and false labels. According to the description, every SARM gets the lowest rating at the end.
| Studies | Kind of study | Who was studied | People | Duration | Dose as studied | Who paid |
|---|---|---|---|---|---|---|
| The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men. | Random groups | Healthy men | 76 | 3 wk | 0.1, 0.3 or 1.0 mg daily | Unknown |
We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.
