Graded
Ministerstwo zdrowia USA opublikowało projekt zasad, według którego nie będzie ścigać aptek przygotowujących BPC-157 na receptę dla konkretnej osoby, dopóki FDA nie zdecyduje w przepisach. To nadal nie jest dopuszczony lek.
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GHRP-6

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Prace naukowe

BadaniaRodzaj badaniaRok
Phase III Open-Label, Randomized Clinical Trial of Epidermal Growth Factor and Growth Hormone Releasing Hexapeptide in Acute Ischemic Stroke.J Clin NeurosciZ losowaniem grup2026
Insulinotropic action of bombesin-like peptides mediated by gastrin-releasing peptide receptors in steers.J Anim SciZ losowaniem grup2016
Bombesin-like peptides stimulate growth hormone secretion mediated by the gastrin-releasing peptide receptor in cattle.PeptidesZ losowaniem grup2012
Effects of ghrelin, growth hormone-releasing peptide-6, and growth hormone-releasing hormone on growth hormone, adrenocorticotropic hormone, and cortisol release in type 1 diabetes mellitus.MetabolismZ losowaniem grup2010
Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6).Clin Endocrinol (Oxf)Z losowaniem grup2010
Decreased ghrelin-induced GH release in thyrotoxicosis: comparison with GH-releasing peptide-6 (GHRP-6) and GHRH.PituitaryZ losowaniem grup2007
GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing's disease: comparison with DDAVP.J Endocrinol InvestZ losowaniem grup2003
Effects of growth hormone-releasing peptides in healthy dogs and in dogs with pituitary-dependent hyperadrenocorticism.Mol Cell EndocrinolZ losowaniem grup2002
Effects of fasting and pegvisomant on the GH-releasing hormone and GH-releasing peptide-6 stimulated growth hormone secretion.Clin Endocrinol (Oxf)Z losowaniem grup2001
Acute dexamethasone administration enhances GH responsiveness to GH releasing peptide-6 (GHRP-6) in man.Clin Endocrinol (Oxf)Z losowaniem grup1999
Growth hormone (GH) response to GH-releasing peptide-6 and GH-releasing hormone in normal-weight and overweight patients with non-insulin-dependent diabetes mellitus.MetabolismZ losowaniem grup1999
Tyr-Ala-Hexarelin, a synthetic octapeptide, possesses the same endocrine activities of Hexarelin and GHRP-2 in humans.J Endocrinol InvestZ losowaniem grup1999
Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.J Clin Endocrinol MetabZ losowaniem grup1998
Different effects of growth hormone releasing peptide (GHRP-6) and GH-releasing hormone on GH release in endogenous and exogenous hypercortisolism.Clin Endocrinol (Oxf)Z losowaniem grup1997
Growth hormone responses to GH-releasing peptide (GHRP-6) in hypothyroidism.Clin Endocrinol (Oxf)Z losowaniem grup1997
Influence of endogenous cholinergic tone and growth hormone-releasing peptide-6 on exercise induced growth hormone release.Clin Endocrinol (Oxf)Z losowaniem grup1997
Hexarelin, a synthetic growth hormone releasing peptide, stimulates prolactin secretion in acromegalic but not in hyperprolactinaemic patients.Clin Endocrinol (Oxf)Z losowaniem grup1996
The effect of an opiate antagonist on the hormonal changes induced by hexarelin.Clin Endocrinol (Oxf)Z losowaniem grup1995
Comparison of the effects of growth hormone-releasing hormone and hexarelin, a novel growth hormone-releasing peptide-6 analog, on growth hormone secretion in humans with or without glucocorticoid excess.J EndocrinolZ losowaniem grup1995
Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man.NeuroendocrinologyZ losowaniem grup1995
Growth hormone secretion after the administration of GHRP-6 or GHRH combined with GHRP-6 does not decline in late adulthood.Clin Endocrinol (Oxf)Z losowaniem grup1995
Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.Eur J Pharm SciBez losowania grup2013
Effects of ghrelin, GH-releasing peptide-6 (GHRP-6) and GHRH on GH, ACTH and cortisol release in hyperthyroidism before and after treatment.PituitaryBez losowania grup2010
Diagnosis of adrenal insufficiency using the GHRP-6 Test: comparison with the insulin tolerance test in patients with hypothalamic-pituitary-adrenal disease.Horm Metab ResBez losowania grup2010
Ghrelin and GHRP-6-induced ACTH and cortisol release in thyrotoxicosis.PituitaryBez losowania grup2009
Association between tumoral GH-releasing peptide receptor type 1a mRNA expression and in vivo response to GH-releasing peptide-6 in ACTH-dependent Cushing's syndrome patients.Eur J EndocrinolBez losowania grup2008
Decreased GH secretion and enhanced ACTH and cortisol release after ghrelin administration in Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6) and GHRH.PituitaryBez losowania grup2006
Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers.PsychoneuroendocrinologyBez losowania grup2004
Growth hormone response to GHRH + GHRP-6 in type 2 diabetes during euglycemic and hyperglycemic clamp.Diabetes Res Clin PractBez losowania grup2004
Comparison between insulin tolerance test, growth hormone (GH)-releasing hormone (GHRH), GHRH plus acipimox and GHRH plus GH-releasing peptide-6 for the diagnosis of adult GH deficiency in normal subjects, obese and hypopituitary patients.Eur J EndocrinolBez losowania grup2003
Growth-hormone response to combined stimulation with GHRH plus GH-releasing peptide-6 in obese patients with polycystic ovary syndrome before and after short-term fasting.J Endocrinol InvestBez losowania grup2003
GH-releasing peptide (GHRP-6)-induced ACTH release in patients with addison's disease: effect of glucocorticoid withdrawal.J Endocrinol InvestBez losowania grup2003
Physical activity or food intake prior to testing did not affect the reproducibility of GH secretion elicited by GH releasing hormone plus GH-releasing hexapeptide in normal adult subjects.Clin Endocrinol (Oxf)Bez losowania grup2002
GH-releasing hormone and GH-releasing peptide-6 for diagnostic testing in GH-deficient adults.LancetBez losowania grup2000
Effects of short-term glucocorticoid deprivation on growth hormone (GH) response to GH-releasing peptide-6: studies in normal men and in patients with adrenal insufficiency.J Clin Endocrinol MetabBez losowania grup2000
Effects of growth hormone-releasing peptide-6 on the nocturnal secretion of GH, ACTH and cortisol and on the sleep EEG in man: role of routes of administration.J NeuroendocrinolBez losowania grup1999
Preserved growth hormone (GH) secretion in aged and very old subjects after testing with the combined stimulus GH-releasing hormone plus GH-releasing hexapeptide-6.J Clin Endocrinol MetabBez losowania grup1998
Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression.J Clin Endocrinol MetabBez losowania grup1996
Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli.J Clin Endocrinol MetabBez losowania grup1996
Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection.J Clin Endocrinol MetabBez losowania grup1995
Growth hormone-releasing effect of oral growth hormone-releasing peptide 6 (GHRP-6) administration in children with short stature.Eur J EndocrinolBez losowania grup1995
Growth hormone (GH) responses to the combined administration of GH-releasing hormone plus GH-releasing peptide 6 in adults with GH deficiency.Eur J EndocrinolBez losowania grup1995
Growth hormone-releasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal aging.Eur J EndocrinolBez losowania grup1994
Arginine enhances the growth hormone-releasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration.J Endocrinol InvestBez losowania grup1994
Growth hormone response in man to L-692,429, a novel nonpeptide mimic of growth hormone-releasing peptide-6.J Clin Endocrinol MetabBez losowania grup1993
Anterior cervical osteophyte-related dysphagia in a long-term growth hormone user: a case report.Front SurgOpisy przypadków2026
In vivo response to growth hormone-releasing peptide-6 in adrenocorticotropin-dependent Cushing's syndrome by lung carcinoid tumor is associated with growth hormone secretagogue receptor type 1a mRNA expression.J Endocrinol InvestOpisy przypadków2007
Transient hypogonadotropic hypogonadism in an amateur kickboxer after head trauma.J Endocrinol InvestOpisy przypadków2007
Acromegaly and Cushing's syndrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: in vitro responses to GHRH and GHRP-6.Clin Endocrinol (Oxf)Opisy przypadków1998
Pituitary enlargement due to primary hypothyroidism: growth hormone response to GHRH, GHRP-6 and GHRH plus GHRP-6.J Pediatr Endocrinol MetabOpisy przypadków1996
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.Sex Med RevPrzegląd badań2026
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Front Endocrinol (Lausanne)Przegląd badań2026
Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior.Pharmacol ResPrzegląd badań2021
Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36).BiomedicinesPrzegląd badań2020
Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Transl Androl UrolPrzegląd badań2020
The Safety and Efficacy of Growth Hormone Secretagogues.Sex Med RevPrzegląd badań2018
Water-in-oil microemulsions for effective transdermal delivery of proteins.Expert Opin Drug DelivPrzegląd badań2011
Diagnosis of adult GH deficiency.Growth Horm IGF ResPrzegląd badań2008
Diagnosis of adult GH deficiency.PituitaryPrzegląd badań2008
Growth hormone levels in the diagnosis of growth hormone deficiency in adulthood.PituitaryPrzegląd badań2007
Physiology of ghrelin and related peptides.Domest Anim EndocrinolPrzegląd badań2005
Update on the diagnosis of GH deficiency in adults.Eur J EndocrinolPrzegląd badań2003
Research progress in the stimulatory inputs regulating growth hormone (GH) secretion.Comp Biochem Physiol B Biochem Mol BiolPrzegląd badań2002
Growth hormone secretagogue receptor family members and ligands.EndocrinePrzegląd badań2001
Neuroregulation of growth hormone secretion in domestic animals.Domest Anim EndocrinolPrzegląd badań2001
Physiology and possible pathology of growth hormone secretagogues.J Pediatr Endocrinol MetabPrzegląd badań2001
Growth hormone-releasing peptides and the cardiovascular system.Ann Endocrinol (Paris)Przegląd badań2000
Growth hormone in obesity.Int J Obes Relat Metab DisordPrzegląd badań1999
Growth hormone secretagogues: the clinical future.Horm ResPrzegląd badań1999
Orally active growth hormone secretagogues: state of the art and clinical perspectives.Ann MedPrzegląd badań1998
New GH secretagogues and potential usefulness in thalassemia.J Pediatr Endocrinol MetabPrzegląd badań1998
Growth hormone-releasing peptides and their analogs.Front NeuroendocrinolPrzegląd badań1998
The development of 'impervious peptides' as growth hormone secretagogues.Acta Paediatr SupplPrzegląd badań1997
Growth hormone-releasing peptides.Eur J EndocrinolPrzegląd badań1997
Role of the new growth hormone-releasing secretagogues in the diagnosis of some hypothalamopituitary pathologies.MetabolismPrzegląd badań1996
Growth hormone releasing hexapeptide-6 (GHRP-6) test in the diagnosis of GH-deficiency.J Pediatr Endocrinol MetabPrzegląd badań1996
Evaluation of pituitary GH reserve with GHRP-6.J Pediatr Endocrinol MetabPrzegląd badań1996
Growth hormone-releasing peptides: clinical and basic aspects.Horm ResPrzegląd badań1996
Regulation of growth hormone secretion by the growth hormone releasing hexapeptide (GHRP-6).J Pediatr EndocrinolPrzegląd badań1993
New diagnostic tests of GH reserve.J Pediatr EndocrinolPrzegląd badań1993
Ghrelin Receptor Blockade Restricts Hepatic Echinococcus granulosus Infection by Suppressing Host Cell Proliferation and Enhancing Fibrotic Encapsulation.Acta ParasitolNa zwierzętach2026
A discovery-based proteomic approach of epidermal growth factor and growth hormone-releasing peptide-6 in a model of acute ischemic stroke.Pharmacol RepNa zwierzętach2026
EGF and GHRP6 Co-Administration Attenuates Cognitive Decline in Preclinical Models: Behavioral and Molecular Evidences.Neurotox ResNa zwierzętach2026
Ghrelin impairs embryo development after ovarian hyperstimulation.J EndocrinolNa zwierzętach2026
Effect of intracerebroventricular (ICV) injection of antimicrobial peptide expressed in the body-2 (LEAP-2) and its interaction with cannabinoid and ghrelin systems on food intake in broiler chickens.Poult SciNa zwierzętach2026
Oral salmon acylated ghrelin increases food intake in common carp (Cyprinus carpio) via ghrelin receptors, likely through sensory nerves rather than systemic absorption.PeptidesNa zwierzętach2026
A novel butyrylcholinesterase inhibitor induces antidepressant, pro-cognitive, and anti-anhedonic effects in Flinders Sensitive Line rats: The role of the ghrelin-dopamine cascade.Biomed PharmacotherNa zwierzętach2025
Subchronic safety assessment of CIGB-500 in beagle dog after repeated daily dose administration over 28 days.Regul Toxicol PharmacolNa zwierzętach2025
Danshen-Chuanxiong-Honghua ameliorates neurological function and inflammation in traumatic brain injury in rats via modulating Ghrelin/GHSR.J EthnopharmacolNa zwierzętach2025
GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival.Vet ResNa zwierzętach2025
Ghrelin suppresses water intake with a different physiological significance from atrial natriuretic peptide in conscious seawater-acclimated eels.J Exp BiolNa zwierzętach2025
Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice.EndocrinologyNa zwierzętach2025
Targeting CD36 With EP 80317 Reduces Remote Inflammatory Response to Hind Limb Ischemia-Reperfusion in Mice.J Biochem Mol ToxicolNa zwierzętach2024
Rikkunshito improves anorexia through ghrelin- and orexin-dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats.Neurogastroenterol MotilNa zwierzętach2024
Ghrelin Modulates Voltage-Gated Ca2+ Channels through Voltage-Dependent and Voltage-Independent Pathways in Rat Gastric Vagal Afferent Neurons.Mol PharmacolNa zwierzętach2024
Ghrelin is essential for lowering blood pressure during torpor.Front Endocrinol (Lausanne)Na zwierzętach2024
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.J Cell BiolNa zwierzętach2024
Ghrelin Improves Glucolipotoxicity-Induced Pancreatic β-Cellular Dysfunction and Apoptosis by Inhibiting Endoplasmic Reticulum Stress-Induced IRE1/JNK Pathway.Discov MedNa zwierzętach2024
Ghrelin misbalance affects mice embryo implantation and pregnancy success by uterine immune dysregulation and nitrosative stress.Front Endocrinol (Lausanne)Na zwierzętach2023
Differential impact of a ghrelin receptor antagonist or inverse agonist in the electrical kindling model of epilepsy.Epilepsy ResNa zwierzętach2023
Meranzin Hydrate Improves Depression-Like Behaviors and Hypomotility via Ghrelin and Neurocircuitry.Chin J Integr MedNa zwierzętach2023
Effect of feeding regimen on circadian activity rhythms of food anticipatory by ghrelin hormone in a pig model.Nutr NeurosciNa zwierzętach2023
Temporal patterns of increased growth hormone secretion in mice after oral administration of L-ornithine: possible involvement of ghrelin receptors.J Vet Med SciNa zwierzętach2022
The neuropeptide cortistatin attenuates Th17 cell response through inhibition of glycolysis via GHSR1.Int ImmunopharmacolNa zwierzętach2022
Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice.PeptidesNa zwierzętach2022
Antagonism of the ghrelin receptor type 1a in the rat brain induces status epilepticus in an electrical kindling model of epilepsy.Psychopharmacology (Berl)Na zwierzętach2022
Ghrelin receptor antagonist attenuated sickness behavior and activation of HPA-axis induced by immunological challenge in male rats.Life SciNa zwierzętach2022
Growth hormone secretagogue peptide-6 enhances oreochromicins transcription and antimicrobial activity in tilapia (Oreochromis sp.).Fish Shellfish ImmunolNa zwierzętach2021
Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken.Arch Razi InstNa zwierzętach2021
Therapeutic effects of acylated ghrelin-specific receptor GHS-R1a antagonist in islet transplantation.Sci RepNa zwierzętach2021
The active fragments of ghrelin cross the blood-brain barrier and enter the brain to produce antinociceptive effects after systemic administration.Can J Physiol PharmacolNa zwierzętach2021
Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.PeptidesNa zwierzętach2021
A quantitative UHPLC-MS/MS method for the growth hormone-releasing peptide-6 determination in complex biological matrices and transdermal formulations.TalantaNa zwierzętach2021
Ghrelin antagonist D-Lys3-GHRP-6 counteract ghrelin effects in bovine cumulus-oocytes complexes matured in vitro.Reprod Domest AnimNa zwierzętach2021
Acylated Ghrelin Attenuates l-Thyroxin-induced Cardiac Damage in Rats by Antioxidant and Anti-inflammatory Effects and Downregulating Components of the Cardiac Renin-angiotensin System.J Cardiovasc PharmacolNa zwierzętach2021
Acylated ghrelin protects against doxorubicin-induced nephropathy by activating silent information regulator 1.Basic Clin Pharmacol ToxicolNa zwierzętach2021
The role of central corticotrophin-releasing factor receptor signalling in plasma glucose maintenance through ghrelin secretion in calorie-restricted mice.J NeuroendocrinolNa zwierzętach2021
Ghrelin antagonist overrides the mRNA expression of NPY in hypothalamus in feed restricted ewes.PLoS OneNa zwierzętach2020
D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors.Physiol BehavNa zwierzętach2020
Ghrelin acts in the brain to block colonic hyperpermeability in response to lipopolysaccharide through the vagus nerve.NeuropharmacologyNa zwierzętach2020
Atheroprotective and atheroregressive potential of azapeptide derivatives of GHRP-6 as selective CD36 ligands in apolipoprotein E-deficient mice.AtherosclerosisNa zwierzętach2020
Ghrelin inhibits autonomic response to gastric distension in rats by acting on vagal pathway.Sci RepNa zwierzętach2020
Estradiol Replacement Improves High-Fat Diet-Induced Obesity by Suppressing the Action of Ghrelin in Ovariectomized Rats.NutrientsNa zwierzętach2020
Chronic ghrelin administration suppresses IKK/NF-κB/BACE1 mediated Aβ production in primary neurons and improves cognitive function via upregulation of PP1 in STZ-diabetic rats.Neurobiol Learn MemNa zwierzętach2020
Hemostatic effect of acylated ghrelin in control and sleeve gastrectomy-induced rats: mechanisms of action.Arch Physiol BiochemNa zwierzętach2020
Rikkunshito Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through Ghrelin Receptors in Murine Small Intestine.DigestionNa zwierzętach2020
Ghrelin fiber projections from the hypothalamic arcuate nucleus into the dorsal vagal complex and the regulation of glycolipid metabolism.NeuropeptidesNa zwierzętach2019
Acylated Ghrelin Protects the Hearts of Rats from Doxorubicin-Induced Fas/FasL Apoptosis by Stimulating SERCA2a Mediated by Activation of PKA and Akt.Cardiovasc ToxicolNa zwierzętach2019
Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model.J NeuroendocrinolNa zwierzętach2019
Inhibition of Ghrelin Activity by Receptor Antagonist [d-Lys-3] GHRP-6 Attenuates Alcohol-Induced Hepatic Steatosis by Regulating Hepatic Lipid Metabolism.BiomoleculesNa zwierzętach2019
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.NeuropharmacologyNa zwierzętach2019
Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1.Naunyn Schmiedebergs Arch PharmacolNa zwierzętach2019
Ghrelin and electrical stimulating the lateral hypothalamus area regulated the discharges of gastric distention neurons via the dorsal vagal complex in cisplatin-treated rats.Gen Comp EndocrinolNa zwierzętach2019
Ghrelin in rat pancreatic islets decreases islet blood flow.Am J Physiol Endocrinol MetabNa zwierzętach2019
Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin.J Cyst FibrosNa zwierzętach2019
The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.Mol CellsNa zwierzętach2019
Chronic predator stress in female mice reduces primordial follicle numbers: implications for the role of ghrelin.J EndocrinolNa zwierzętach2019
Unacylated ghrelin stimulates steroidogenesis in lean rats and reverses reproductive dysfunction in high fat diet-fed rats.Syst Biol Reprod MedNa zwierzętach2019
The antinociceptive effects and molecular mechanisms of ghrelin(1-7)-NH2 at the supraspinal level in acute pain in mice.Brain Res BullNa zwierzętach2019
New Metabolic Influencer on Oxytocin Release: The Ghrelin.MoleculesNa zwierzętach2019
Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling.NeuropharmacologyW probówce2016
Ghrelin and nicotine stimulate equally the dopamine release in the rat amygdala.Neurochem ResW probówce2013
Ghrelin modulates lateral amygdala neuronal firing and blocks acquisition for conditioned taste aversion.PLoS OneW probówce2013
Ghrelin increases GABAergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala.NeuropsychopharmacologyW probówce2013
Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium.PLoS OneW probówce2012
Ghrelin postsynaptically depolarizes dorsal raphe neurons in rats in vitro.PeptidesW probówce2011
Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.Invest Ophthalmol Vis SciW probówce2011
Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β pathways.Exp NeurolW probówce2011
In vitro and in vivo effect of acylated and unacylated ghrelin on neonatal glucose homeostasis.Pediatr ResW probówce2010
Electrophysiological effects of ghrelin on pedunculopontine tegmental neurons in rats: An in vitro study.PeptidesW probówce2009
Ghrelin and obestatin: different role in fetal lung development?PeptidesW probówce2008
Therapeutic effects of ghrelin and growth hormone releasing peptide 6 on gastroparesis in streptozotocin-induced diabetic guinea pigs in vivo and in vitro.Chin Med J (Engl)W probówce2008
Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile rats: an in vitro study.PeptidesW probówce2008
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.DiabetesW probówce2008
Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro.PeptidesW probówce2007
Ghrelin augments afferent response to distension in rat isolated jejunum.Neurogastroenterol MotilW probówce2006
The contractile effect of the ghrelin receptor antagonist, D-Lys3-GHRP-6, in rat fundic strips is mediated through 5-HT receptors.Eur J PharmacolW probówce2006
Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.Eur J PharmacolW probówce2005
In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish.Am J Physiol Regul Integr Comp PhysiolW probówce2004
Stimulatory effect of ghrelin on isolated porcine somatotropes.NeuroendocrinologyW probówce2003
Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum.J Pharmacol Exp TherW probówce2003
GH-releasing peptide-6 overcomes refractoriness of somatotropes to GHRH after feeding.J EndocrinolW probówce2001
GHRP-6-induced changes in electrical activity of single cells in the arcuate, ventromedial and periventricular nucleus neurones [correction of nuclei] of a hypothalamic slice preparation in vitro.J NeuroendocrinolW probówce1999
A new series of highly potent growth hormone-releasing peptides derived from ipamorelin.J Med ChemW probówce1998
Histones as extracellular messengers: effects on growth hormone secretion.Cell Biol IntW probówce1997
In vitro characterization of four novel classes of growth hormone-releasing peptide.EndocrinologyW probówce1995
Growth hormone releasing hexapeptide (GHRP-6) activates the inositol (1,4,5)-trisphosphate/diacylglycerol pathway in rat anterior pituitary cells.J Recept Signal Transduct ResW probówce1995
Topical delivery of growth hormone releasing peptide using liposomal systems: an in vitro study using hairless mouse skin.Life SciW probówce1995
Ghrelin attenuates hypoxia-induced mitochondrial oxidative stress damage in HTR-8/SVneo trophoblasts.Tissue CellInna praca2026
Activation of the nucleus nuclear factor erythroid 2-related factor 2ghrelin/growth hormone secretagogue receptor 1a signaling by Yueju pill confers cardioprotective and antidepressant effects.J Tradit Chin MedInna praca2026
The Ghrelin/GHSR-1a Axis Attenuates Preeclampsia-like Features with Decidual Macrophage Reprogramming and Improved Placental Remodeling.BiomoleculesInna praca2026
Growth Hormone-Releasing Peptide-6 (GHRP-6) Ameliorates Post-Infarct Ventricular Remodeling and Systolic Dysfunction in a Model of Permanent Coronary Ligation.Pharmaceuticals (Basel)Inna praca2026
Growth hormone releasing peptide-6 (GHRP-6) ameliorates acute lung injury and its subsequent evolvement to interstitial fibrosis.Int ImmunopharmacolInna praca2026
Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation.J NanobiotechnologyInna praca2025
Aza-Isotryptophan: Synthesis, Pictet-Spengler Chemistry, Incorporation and Conformational Analysis in Peptides, and Activity in Modulators of the Cluster of Differentiation-36 Receptor.J Med ChemInna praca2025
Assessing The Effectiveness of Growth Hormone Releasing Protein-6 in Improving Human Oocyte Maturation and Meiotic Progression in In Vitro Maturation Culture Media.Int J Fertil SterilInna praca2025
The Ghrelin Analog GHRP-6, Delivered Through Aquafeeds, Modulates the Endocrine and Immune Responses of Sparus aurata Following IFA Treatment.Biology (Basel)Inna praca2025
Ghrelin promotes neurologic recovery and neurogenesis in the chronic phase after experimental stroke.Neurol Res PractInna praca2025
Changes in Locomotor Activity Observed During Acute Nicotine Withdrawal Can Be Attenuated by Ghrelin and GHRP-6 in Rats.BiomedicinesInna praca2025
Novel chimeric peptides based on endomorphins and ghrelin receptor antagonist produced supraspinal antinociceptive effects with reduced acute tolerance in mice.BiochimieInna praca2025
Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.PLoS Negl Trop DisInna praca2024
Ghrelin alleviates intestinal ischemia-reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway.FASEB JInna praca2024
Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms.Front PharmacolInna praca2024
Ghrelin regulates the endoplasmic reticulum stress signalling pathway in gestational diabetes mellitus.Biochem Biophys Res CommunInna praca2024
In-house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH-related peptides.Biomed ChromatogrInna praca2023
Ghrelin improves cognition via activation of the cAMP- CREB signalling pathway in depressed male C57BL/6J mice.Int J NeurosciInna praca2023
Desacylghrelin modulates GHS-R1 receptor expression and cell differentiation in placental BeWo cells.Mol Cell EndocrinolInna praca2023
Ghrelin Amplifies the Nicotine-Induced Release of Dopamine in the Bed Nucleus of Stria Terminalis (BNST).BiomedicinesInna praca2023
Inhibition of ghrelin activity by the receptor antagonist [D-Lys3]-GHRP-6 enhances hepatic fatty acid oxidation and gluconeogenesis in a growing pig model.PeptidesInna praca2023
The effects and mechanisms of ghrelin upon angiogenesis in human coronary artery endothelial cells under hypoxia.PeptidesInna praca2023
Ghrelin Downregulates Lipopolysaccharide/ Leptin-Induced MUC5AC Expression in Human Nasal Epithelial Cells.Clin Exp OtorhinolaryngolInna praca2023
Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance.Iran J Basic Med SciInna praca2022
Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067.Sci RepInna praca2022
Antagonization of Ghrelin Suppresses Muscle Protein Deposition by Altering Gut Microbiota and Serum Amino Acid Composition in a Pig Model.Biology (Basel)Inna praca2022
Enteral nutrition alleviated lipopolysaccharides-induced hypercatabolism through ghrelin/GHS-R1α-POMC.Biochem Biophys Res CommunInna praca2022
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor.Nat CommunInna praca2021
Ghrelin Affects Gastric Cancer Progression by Activating AMPK Signaling Pathway.Biochem GenetInna praca2021
Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats.Can J Physiol PharmacolInna praca2021
Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis.Front PharmacolInna praca2021
Ultra-Fast Computation of Excited-States Spectra for Large Systems: Ultraviolet and Fluorescence Spectra of Proteins.Interdiscip SciInna praca2021
Mass spectrometric and kinetics characterization of modified species of Growth Hormone Releasing Hexapeptide generated under thermal stress in different pH and buffers.J Pharm Biomed AnalInna praca2021
Ghrelin in the lateral parabrachial nucleus influences the excitability of glucosensing neurons, increases food intake and body weight.Endocr ConnectInna praca2020
In silico strategy for detailing the binding modes of a novel family of peptides proven as ghrelin receptor agonists.J Mol ModelInna praca2020
Fully automated dried blood spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS.Anal Bioanal ChemInna praca2020
Ghrelin up-regulates cartilage-specific genes via the ERK/STAT3 pathway in chondrocytes of patients with adolescent idiopathic scoliosis.Biochem Biophys Res CommunInna praca2019
Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE.Free Radic Biol MedInna praca2019
Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway.Anal Cell Pathol (Amst)Inna praca2019
Inhibitor of ghrelin receptor reverses gefitinib resistance in lung cancer.Hum CellInna praca2019
Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6.EndocrineInna praca2019
Characterization of a third ghrelin receptor, GHS-R3a, in channel catfish reveals novel expression patterns and a high affinity for homologous ligand.Comp Biochem Physiol A Mol Integr PhysiolInna praca2019
Effects of Ghrelin on the Apoptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocyte MH7A Cells.Biol Pharm BullInna praca2019
Glycine-modified growth hormone secretagogues identified in seized doping material.Drug Test AnalInna praca2019
Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists.FASEB JInna praca2019
A Linear Fragment of Unacylated Ghrelin (UAG6-13) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner.Front Endocrinol (Lausanne)Inna praca2018
Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism.Front Endocrinol (Lausanne)Inna praca2018
Azasulfurylpeptide Modulation of CD36-Mediated Inflammation Without Effect on Neovascularization.BiomedicinesInna praca2018
A stable meta-carborane enables the generation of boron-rich peptide agonists targeting the ghrelin receptor.J Pept SciInna praca2018
Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor.Eur J Med ChemInna praca2018
Ghrelin Stimulates Endothelial Cells Angiogenesis through Extracellular Regulated Protein Kinases (ERK) Signaling Pathway.Int J Mol SciInna praca2018
Growth hormone-releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study.Int Wound JInna praca2018
Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via Mediating Ghrelin and GABAA Receptor Signaling Pathway.Front PharmacolInna praca2018
A polypeptide-mediated synthesis of green fluorescent gold nanoclusters for Fe3+ sensing and bioimaging.J Colloid Interface SciInna praca2017
Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.Am J Mens HealthInna praca2017
Azapeptide Synthesis Methods for Expanding Side-Chain Diversity for Biomedical Applications.Acc Chem ResInna praca2017
Diversity-Oriented Synthesis of Cyclic Azapeptides by A3 -Macrocyclization Provides High-Affinity CD36-Modulating Peptidomimetics.Angew Chem Int Ed EnglInna praca2017
Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.Biomed PharmacotherInna praca2017
Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems.Cell Physiol BiochemInna praca2017

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