| Phase III Open-Label, Randomized Clinical Trial of Epidermal Growth Factor and Growth Hormone Releasing Hexapeptide in Acute Ischemic Stroke.J Clin Neurosci | Random groups | 2026 |
| Insulinotropic action of bombesin-like peptides mediated by gastrin-releasing peptide receptors in steers.J Anim Sci | Random groups | 2016 |
| Bombesin-like peptides stimulate growth hormone secretion mediated by the gastrin-releasing peptide receptor in cattle.Peptides | Random groups | 2012 |
| Effects of ghrelin, growth hormone-releasing peptide-6, and growth hormone-releasing hormone on growth hormone, adrenocorticotropic hormone, and cortisol release in type 1 diabetes mellitus.Metabolism | Random groups | 2010 |
| Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6).Clin Endocrinol (Oxf) | Random groups | 2010 |
| Decreased ghrelin-induced GH release in thyrotoxicosis: comparison with GH-releasing peptide-6 (GHRP-6) and GHRH.Pituitary | Random groups | 2007 |
| GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing's disease: comparison with DDAVP.J Endocrinol Invest | Random groups | 2003 |
| Effects of growth hormone-releasing peptides in healthy dogs and in dogs with pituitary-dependent hyperadrenocorticism.Mol Cell Endocrinol | Random groups | 2002 |
| Effects of fasting and pegvisomant on the GH-releasing hormone and GH-releasing peptide-6 stimulated growth hormone secretion.Clin Endocrinol (Oxf) | Random groups | 2001 |
| Acute dexamethasone administration enhances GH responsiveness to GH releasing peptide-6 (GHRP-6) in man.Clin Endocrinol (Oxf) | Random groups | 1999 |
| Growth hormone (GH) response to GH-releasing peptide-6 and GH-releasing hormone in normal-weight and overweight patients with non-insulin-dependent diabetes mellitus.Metabolism | Random groups | 1999 |
| Tyr-Ala-Hexarelin, a synthetic octapeptide, possesses the same endocrine activities of Hexarelin and GHRP-2 in humans.J Endocrinol Invest | Random groups | 1999 |
| Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.J Clin Endocrinol Metab | Random groups | 1998 |
| Different effects of growth hormone releasing peptide (GHRP-6) and GH-releasing hormone on GH release in endogenous and exogenous hypercortisolism.Clin Endocrinol (Oxf) | Random groups | 1997 |
| Growth hormone responses to GH-releasing peptide (GHRP-6) in hypothyroidism.Clin Endocrinol (Oxf) | Random groups | 1997 |
| Influence of endogenous cholinergic tone and growth hormone-releasing peptide-6 on exercise induced growth hormone release.Clin Endocrinol (Oxf) | Random groups | 1997 |
| Hexarelin, a synthetic growth hormone releasing peptide, stimulates prolactin secretion in acromegalic but not in hyperprolactinaemic patients.Clin Endocrinol (Oxf) | Random groups | 1996 |
| The effect of an opiate antagonist on the hormonal changes induced by hexarelin.Clin Endocrinol (Oxf) | Random groups | 1995 |
| Comparison of the effects of growth hormone-releasing hormone and hexarelin, a novel growth hormone-releasing peptide-6 analog, on growth hormone secretion in humans with or without glucocorticoid excess.J Endocrinol | Random groups | 1995 |
| Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol release in normal man.Neuroendocrinology | Random groups | 1995 |
| Growth hormone secretion after the administration of GHRP-6 or GHRH combined with GHRP-6 does not decline in late adulthood.Clin Endocrinol (Oxf) | Random groups | 1995 |
| Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.Eur J Pharm Sci | No random groups | 2013 |
| Effects of ghrelin, GH-releasing peptide-6 (GHRP-6) and GHRH on GH, ACTH and cortisol release in hyperthyroidism before and after treatment.Pituitary | No random groups | 2010 |
| Diagnosis of adrenal insufficiency using the GHRP-6 Test: comparison with the insulin tolerance test in patients with hypothalamic-pituitary-adrenal disease.Horm Metab Res | No random groups | 2010 |
| Ghrelin and GHRP-6-induced ACTH and cortisol release in thyrotoxicosis.Pituitary | No random groups | 2009 |
| Association between tumoral GH-releasing peptide receptor type 1a mRNA expression and in vivo response to GH-releasing peptide-6 in ACTH-dependent Cushing's syndrome patients.Eur J Endocrinol | No random groups | 2008 |
| Decreased GH secretion and enhanced ACTH and cortisol release after ghrelin administration in Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6) and GHRH.Pituitary | No random groups | 2006 |
| Hexarelin decreases slow-wave sleep and stimulates the secretion of GH, ACTH, cortisol and prolactin during sleep in healthy volunteers.Psychoneuroendocrinology | No random groups | 2004 |
| Growth hormone response to GHRH + GHRP-6 in type 2 diabetes during euglycemic and hyperglycemic clamp.Diabetes Res Clin Pract | No random groups | 2004 |
| Comparison between insulin tolerance test, growth hormone (GH)-releasing hormone (GHRH), GHRH plus acipimox and GHRH plus GH-releasing peptide-6 for the diagnosis of adult GH deficiency in normal subjects, obese and hypopituitary patients.Eur J Endocrinol | No random groups | 2003 |
| Growth-hormone response to combined stimulation with GHRH plus GH-releasing peptide-6 in obese patients with polycystic ovary syndrome before and after short-term fasting.J Endocrinol Invest | No random groups | 2003 |
| GH-releasing peptide (GHRP-6)-induced ACTH release in patients with addison's disease: effect of glucocorticoid withdrawal.J Endocrinol Invest | No random groups | 2003 |
| Physical activity or food intake prior to testing did not affect the reproducibility of GH secretion elicited by GH releasing hormone plus GH-releasing hexapeptide in normal adult subjects.Clin Endocrinol (Oxf) | No random groups | 2002 |
| GH-releasing hormone and GH-releasing peptide-6 for diagnostic testing in GH-deficient adults.Lancet | No random groups | 2000 |
| Effects of short-term glucocorticoid deprivation on growth hormone (GH) response to GH-releasing peptide-6: studies in normal men and in patients with adrenal insufficiency.J Clin Endocrinol Metab | No random groups | 2000 |
| Effects of growth hormone-releasing peptide-6 on the nocturnal secretion of GH, ACTH and cortisol and on the sleep EEG in man: role of routes of administration.J Neuroendocrinol | No random groups | 1999 |
| Preserved growth hormone (GH) secretion in aged and very old subjects after testing with the combined stimulus GH-releasing hormone plus GH-releasing hexapeptide-6.J Clin Endocrinol Metab | No random groups | 1998 |
| Impaired growth hormone secretion in obese subjects is partially reversed by acipimox-mediated plasma free fatty acid depression.J Clin Endocrinol Metab | No random groups | 1996 |
| Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli.J Clin Endocrinol Metab | No random groups | 1996 |
| Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6), or GHRH plus GHRP-6 in children with neonatal pituitary stalk transection.J Clin Endocrinol Metab | No random groups | 1995 |
| Growth hormone-releasing effect of oral growth hormone-releasing peptide 6 (GHRP-6) administration in children with short stature.Eur J Endocrinol | No random groups | 1995 |
| Growth hormone (GH) responses to the combined administration of GH-releasing hormone plus GH-releasing peptide 6 in adults with GH deficiency.Eur J Endocrinol | No random groups | 1995 |
| Growth hormone-releasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal aging.Eur J Endocrinol | No random groups | 1994 |
| Arginine enhances the growth hormone-releasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration.J Endocrinol Invest | No random groups | 1994 |
| Growth hormone response in man to L-692,429, a novel nonpeptide mimic of growth hormone-releasing peptide-6.J Clin Endocrinol Metab | No random groups | 1993 |
| Anterior cervical osteophyte-related dysphagia in a long-term growth hormone user: a case report.Front Surg | Case reports | 2026 |
| In vivo response to growth hormone-releasing peptide-6 in adrenocorticotropin-dependent Cushing's syndrome by lung carcinoid tumor is associated with growth hormone secretagogue receptor type 1a mRNA expression.J Endocrinol Invest | Case reports | 2007 |
| Transient hypogonadotropic hypogonadism in an amateur kickboxer after head trauma.J Endocrinol Invest | Case reports | 2007 |
| Acromegaly and Cushing's syndrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour: in vitro responses to GHRH and GHRP-6.Clin Endocrinol (Oxf) | Case reports | 1998 |
| Pituitary enlargement due to primary hypothyroidism: growth hormone response to GHRH, GHRP-6 and GHRH plus GHRP-6.J Pediatr Endocrinol Metab | Case reports | 1996 |
| Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.Sex Med Rev | Review of studies | 2026 |
| The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.Front Endocrinol (Lausanne) | Review of studies | 2026 |
| Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior.Pharmacol Res | Review of studies | 2021 |
| Synthesis and Biomedical Potential of Azapeptide Modulators of the Cluster of Differentiation 36 Receptor (CD36).Biomedicines | Review of studies | 2020 |
| Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Transl Androl Urol | Review of studies | 2020 |
| The Safety and Efficacy of Growth Hormone Secretagogues.Sex Med Rev | Review of studies | 2018 |
| Water-in-oil microemulsions for effective transdermal delivery of proteins.Expert Opin Drug Deliv | Review of studies | 2011 |
| Diagnosis of adult GH deficiency.Growth Horm IGF Res | Review of studies | 2008 |
| Diagnosis of adult GH deficiency.Pituitary | Review of studies | 2008 |
| Growth hormone levels in the diagnosis of growth hormone deficiency in adulthood.Pituitary | Review of studies | 2007 |
| Physiology of ghrelin and related peptides.Domest Anim Endocrinol | Review of studies | 2005 |
| Update on the diagnosis of GH deficiency in adults.Eur J Endocrinol | Review of studies | 2003 |
| Research progress in the stimulatory inputs regulating growth hormone (GH) secretion.Comp Biochem Physiol B Biochem Mol Biol | Review of studies | 2002 |
| Growth hormone secretagogue receptor family members and ligands.Endocrine | Review of studies | 2001 |
| Neuroregulation of growth hormone secretion in domestic animals.Domest Anim Endocrinol | Review of studies | 2001 |
| Physiology and possible pathology of growth hormone secretagogues.J Pediatr Endocrinol Metab | Review of studies | 2001 |
| Growth hormone-releasing peptides and the cardiovascular system.Ann Endocrinol (Paris) | Review of studies | 2000 |
| Growth hormone in obesity.Int J Obes Relat Metab Disord | Review of studies | 1999 |
| Growth hormone secretagogues: the clinical future.Horm Res | Review of studies | 1999 |
| Orally active growth hormone secretagogues: state of the art and clinical perspectives.Ann Med | Review of studies | 1998 |
| New GH secretagogues and potential usefulness in thalassemia.J Pediatr Endocrinol Metab | Review of studies | 1998 |
| Growth hormone-releasing peptides and their analogs.Front Neuroendocrinol | Review of studies | 1998 |
| The development of 'impervious peptides' as growth hormone secretagogues.Acta Paediatr Suppl | Review of studies | 1997 |
| Growth hormone-releasing peptides.Eur J Endocrinol | Review of studies | 1997 |
| Role of the new growth hormone-releasing secretagogues in the diagnosis of some hypothalamopituitary pathologies.Metabolism | Review of studies | 1996 |
| Growth hormone releasing hexapeptide-6 (GHRP-6) test in the diagnosis of GH-deficiency.J Pediatr Endocrinol Metab | Review of studies | 1996 |
| Evaluation of pituitary GH reserve with GHRP-6.J Pediatr Endocrinol Metab | Review of studies | 1996 |
| Growth hormone-releasing peptides: clinical and basic aspects.Horm Res | Review of studies | 1996 |
| Regulation of growth hormone secretion by the growth hormone releasing hexapeptide (GHRP-6).J Pediatr Endocrinol | Review of studies | 1993 |
| New diagnostic tests of GH reserve.J Pediatr Endocrinol | Review of studies | 1993 |
| Ghrelin Receptor Blockade Restricts Hepatic Echinococcus granulosus Infection by Suppressing Host Cell Proliferation and Enhancing Fibrotic Encapsulation.Acta Parasitol | In animals | 2026 |
| A discovery-based proteomic approach of epidermal growth factor and growth hormone-releasing peptide-6 in a model of acute ischemic stroke.Pharmacol Rep | In animals | 2026 |
| EGF and GHRP6 Co-Administration Attenuates Cognitive Decline in Preclinical Models: Behavioral and Molecular Evidences.Neurotox Res | In animals | 2026 |
| Ghrelin impairs embryo development after ovarian hyperstimulation.J Endocrinol | In animals | 2026 |
| Effect of intracerebroventricular (ICV) injection of antimicrobial peptide expressed in the body-2 (LEAP-2) and its interaction with cannabinoid and ghrelin systems on food intake in broiler chickens.Poult Sci | In animals | 2026 |
| Oral salmon acylated ghrelin increases food intake in common carp (Cyprinus carpio) via ghrelin receptors, likely through sensory nerves rather than systemic absorption.Peptides | In animals | 2026 |
| A novel butyrylcholinesterase inhibitor induces antidepressant, pro-cognitive, and anti-anhedonic effects in Flinders Sensitive Line rats: The role of the ghrelin-dopamine cascade.Biomed Pharmacother | In animals | 2025 |
| Subchronic safety assessment of CIGB-500 in beagle dog after repeated daily dose administration over 28 days.Regul Toxicol Pharmacol | In animals | 2025 |
| Danshen-Chuanxiong-Honghua ameliorates neurological function and inflammation in traumatic brain injury in rats via modulating Ghrelin/GHSR.J Ethnopharmacol | In animals | 2025 |
| GHSR gene knockout alleviates the liver pathological response in Echinococcus granulosus infection by reducing parasite survival.Vet Res | In animals | 2025 |
| Ghrelin suppresses water intake with a different physiological significance from atrial natriuretic peptide in conscious seawater-acclimated eels.J Exp Biol | In animals | 2025 |
| Intranasal Delivery of a Ghrelin Mimetic Engages the Brain Ghrelin Signaling System in Mice.Endocrinology | In animals | 2025 |
| Targeting CD36 With EP 80317 Reduces Remote Inflammatory Response to Hind Limb Ischemia-Reperfusion in Mice.J Biochem Mol Toxicol | In animals | 2024 |
| Rikkunshito improves anorexia through ghrelin- and orexin-dependent activation of the brain hypothalamus and mesolimbic dopaminergic pathway in rats.Neurogastroenterol Motil | In animals | 2024 |
| Ghrelin Modulates Voltage-Gated Ca2+ Channels through Voltage-Dependent and Voltage-Independent Pathways in Rat Gastric Vagal Afferent Neurons.Mol Pharmacol | In animals | 2024 |
| Ghrelin is essential for lowering blood pressure during torpor.Front Endocrinol (Lausanne) | In animals | 2024 |
| Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells.J Cell Biol | In animals | 2024 |
| Ghrelin Improves Glucolipotoxicity-Induced Pancreatic β-Cellular Dysfunction and Apoptosis by Inhibiting Endoplasmic Reticulum Stress-Induced IRE1/JNK Pathway.Discov Med | In animals | 2024 |
| Ghrelin misbalance affects mice embryo implantation and pregnancy success by uterine immune dysregulation and nitrosative stress.Front Endocrinol (Lausanne) | In animals | 2023 |
| Differential impact of a ghrelin receptor antagonist or inverse agonist in the electrical kindling model of epilepsy.Epilepsy Res | In animals | 2023 |
| Meranzin Hydrate Improves Depression-Like Behaviors and Hypomotility via Ghrelin and Neurocircuitry.Chin J Integr Med | In animals | 2023 |
| Effect of feeding regimen on circadian activity rhythms of food anticipatory by ghrelin hormone in a pig model.Nutr Neurosci | In animals | 2023 |
| Temporal patterns of increased growth hormone secretion in mice after oral administration of L-ornithine: possible involvement of ghrelin receptors.J Vet Med Sci | In animals | 2022 |
| The neuropeptide cortistatin attenuates Th17 cell response through inhibition of glycolysis via GHSR1.Int Immunopharmacol | In animals | 2022 |
| Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice.Peptides | In animals | 2022 |
| Antagonism of the ghrelin receptor type 1a in the rat brain induces status epilepticus in an electrical kindling model of epilepsy.Psychopharmacology (Berl) | In animals | 2022 |
| Ghrelin receptor antagonist attenuated sickness behavior and activation of HPA-axis induced by immunological challenge in male rats.Life Sci | In animals | 2022 |
| Growth hormone secretagogue peptide-6 enhances oreochromicins transcription and antimicrobial activity in tilapia (Oreochromis sp.).Fish Shellfish Immunol | In animals | 2021 |
| Role of Dopaminergic and Cannabinoidergic Receptors on Ghrelin-Induced Hypophagia in 5-Day-Old Broiler Chicken.Arch Razi Inst | In animals | 2021 |
| Therapeutic effects of acylated ghrelin-specific receptor GHS-R1a antagonist in islet transplantation.Sci Rep | In animals | 2021 |
| The active fragments of ghrelin cross the blood-brain barrier and enter the brain to produce antinociceptive effects after systemic administration.Can J Physiol Pharmacol | In animals | 2021 |
| Ghrelin ameliorates cardiac fibrosis after myocardial infarction by regulating the Nrf2/NADPH/ROS pathway.Peptides | In animals | 2021 |
| A quantitative UHPLC-MS/MS method for the growth hormone-releasing peptide-6 determination in complex biological matrices and transdermal formulations.Talanta | In animals | 2021 |
| Ghrelin antagonist D-Lys3-GHRP-6 counteract ghrelin effects in bovine cumulus-oocytes complexes matured in vitro.Reprod Domest Anim | In animals | 2021 |
| Acylated Ghrelin Attenuates l-Thyroxin-induced Cardiac Damage in Rats by Antioxidant and Anti-inflammatory Effects and Downregulating Components of the Cardiac Renin-angiotensin System.J Cardiovasc Pharmacol | In animals | 2021 |
| Acylated ghrelin protects against doxorubicin-induced nephropathy by activating silent information regulator 1.Basic Clin Pharmacol Toxicol | In animals | 2021 |
| The role of central corticotrophin-releasing factor receptor signalling in plasma glucose maintenance through ghrelin secretion in calorie-restricted mice.J Neuroendocrinol | In animals | 2021 |
| Ghrelin antagonist overrides the mRNA expression of NPY in hypothalamus in feed restricted ewes.PLoS One | In animals | 2020 |
| D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors.Physiol Behav | In animals | 2020 |
| Ghrelin acts in the brain to block colonic hyperpermeability in response to lipopolysaccharide through the vagus nerve.Neuropharmacology | In animals | 2020 |
| Atheroprotective and atheroregressive potential of azapeptide derivatives of GHRP-6 as selective CD36 ligands in apolipoprotein E-deficient mice.Atherosclerosis | In animals | 2020 |
| Ghrelin inhibits autonomic response to gastric distension in rats by acting on vagal pathway.Sci Rep | In animals | 2020 |
| Estradiol Replacement Improves High-Fat Diet-Induced Obesity by Suppressing the Action of Ghrelin in Ovariectomized Rats.Nutrients | In animals | 2020 |
| Chronic ghrelin administration suppresses IKK/NF-κB/BACE1 mediated Aβ production in primary neurons and improves cognitive function via upregulation of PP1 in STZ-diabetic rats.Neurobiol Learn Mem | In animals | 2020 |
| Hemostatic effect of acylated ghrelin in control and sleeve gastrectomy-induced rats: mechanisms of action.Arch Physiol Biochem | In animals | 2020 |
| Rikkunshito Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through Ghrelin Receptors in Murine Small Intestine.Digestion | In animals | 2020 |
| Ghrelin fiber projections from the hypothalamic arcuate nucleus into the dorsal vagal complex and the regulation of glycolipid metabolism.Neuropeptides | In animals | 2019 |
| Acylated Ghrelin Protects the Hearts of Rats from Doxorubicin-Induced Fas/FasL Apoptosis by Stimulating SERCA2a Mediated by Activation of PKA and Akt.Cardiovasc Toxicol | In animals | 2019 |
| Growth hormone secretagogue receptor signalling affects high-fat intake independently of plasma levels of ghrelin and LEAP2, in a 4-day binge eating model.J Neuroendocrinol | In animals | 2019 |
| Inhibition of Ghrelin Activity by Receptor Antagonist [d-Lys-3] GHRP-6 Attenuates Alcohol-Induced Hepatic Steatosis by Regulating Hepatic Lipid Metabolism.Biomolecules | In animals | 2019 |
| The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice.Neuropharmacology | In animals | 2019 |
| Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1.Naunyn Schmiedebergs Arch Pharmacol | In animals | 2019 |
| Ghrelin and electrical stimulating the lateral hypothalamus area regulated the discharges of gastric distention neurons via the dorsal vagal complex in cisplatin-treated rats.Gen Comp Endocrinol | In animals | 2019 |
| Ghrelin in rat pancreatic islets decreases islet blood flow.Am J Physiol Endocrinol Metab | In animals | 2019 |
| Incretin dysfunction and hyperglycemia in cystic fibrosis: Role of acyl-ghrelin.J Cyst Fibros | In animals | 2019 |
| The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.Mol Cells | In animals | 2019 |
| Chronic predator stress in female mice reduces primordial follicle numbers: implications for the role of ghrelin.J Endocrinol | In animals | 2019 |
| Unacylated ghrelin stimulates steroidogenesis in lean rats and reverses reproductive dysfunction in high fat diet-fed rats.Syst Biol Reprod Med | In animals | 2019 |
| The antinociceptive effects and molecular mechanisms of ghrelin(1-7)-NH2 at the supraspinal level in acute pain in mice.Brain Res Bull | In animals | 2019 |
| New Metabolic Influencer on Oxytocin Release: The Ghrelin.Molecules | In animals | 2019 |
| Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling.Neuropharmacology | In a lab dish | 2016 |
| Ghrelin and nicotine stimulate equally the dopamine release in the rat amygdala.Neurochem Res | In a lab dish | 2013 |
| Ghrelin modulates lateral amygdala neuronal firing and blocks acquisition for conditioned taste aversion.PLoS One | In a lab dish | 2013 |
| Ghrelin increases GABAergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala.Neuropsychopharmacology | In a lab dish | 2013 |
| Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium.PLoS One | In a lab dish | 2012 |
| Ghrelin postsynaptically depolarizes dorsal raphe neurons in rats in vitro.Peptides | In a lab dish | 2011 |
| Ghrelin modulates physiologic and pathologic retinal angiogenesis through GHSR-1a.Invest Ophthalmol Vis Sci | In a lab dish | 2011 |
| Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β pathways.Exp Neurol | In a lab dish | 2011 |
| In vitro and in vivo effect of acylated and unacylated ghrelin on neonatal glucose homeostasis.Pediatr Res | In a lab dish | 2010 |
| Electrophysiological effects of ghrelin on pedunculopontine tegmental neurons in rats: An in vitro study.Peptides | In a lab dish | 2009 |
| Ghrelin and obestatin: different role in fetal lung development?Peptides | In a lab dish | 2008 |
| Therapeutic effects of ghrelin and growth hormone releasing peptide 6 on gastroparesis in streptozotocin-induced diabetic guinea pigs in vivo and in vitro.Chin Med J (Engl) | In a lab dish | 2008 |
| Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile rats: an in vitro study.Peptides | In a lab dish | 2008 |
| Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.Diabetes | In a lab dish | 2008 |
| Contractile effects of ghrelin-related peptides on the chicken gastrointestinal tract in vitro.Peptides | In a lab dish | 2007 |
| Ghrelin augments afferent response to distension in rat isolated jejunum.Neurogastroenterol Motil | In a lab dish | 2006 |
| The contractile effect of the ghrelin receptor antagonist, D-Lys3-GHRP-6, in rat fundic strips is mediated through 5-HT receptors.Eur J Pharmacol | In a lab dish | 2006 |
| Comparison of the gastroprokinetic effects of ghrelin, GHRP-6 and motilin in rats in vivo and in vitro.Eur J Pharmacol | In a lab dish | 2005 |
| In vitro and in vivo effects of ghrelin on luteinizing hormone and growth hormone release in goldfish.Am J Physiol Regul Integr Comp Physiol | In a lab dish | 2004 |
| Stimulatory effect of ghrelin on isolated porcine somatotropes.Neuroendocrinology | In a lab dish | 2003 |
| Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum.J Pharmacol Exp Ther | In a lab dish | 2003 |
| GH-releasing peptide-6 overcomes refractoriness of somatotropes to GHRH after feeding.J Endocrinol | In a lab dish | 2001 |
| GHRP-6-induced changes in electrical activity of single cells in the arcuate, ventromedial and periventricular nucleus neurones [correction of nuclei] of a hypothalamic slice preparation in vitro.J Neuroendocrinol | In a lab dish | 1999 |
| A new series of highly potent growth hormone-releasing peptides derived from ipamorelin.J Med Chem | In a lab dish | 1998 |
| Histones as extracellular messengers: effects on growth hormone secretion.Cell Biol Int | In a lab dish | 1997 |
| In vitro characterization of four novel classes of growth hormone-releasing peptide.Endocrinology | In a lab dish | 1995 |
| Growth hormone releasing hexapeptide (GHRP-6) activates the inositol (1,4,5)-trisphosphate/diacylglycerol pathway in rat anterior pituitary cells.J Recept Signal Transduct Res | In a lab dish | 1995 |
| Topical delivery of growth hormone releasing peptide using liposomal systems: an in vitro study using hairless mouse skin.Life Sci | In a lab dish | 1995 |
| Ghrelin attenuates hypoxia-induced mitochondrial oxidative stress damage in HTR-8/SVneo trophoblasts.Tissue Cell | Other paper | 2026 |
| Activation of the nucleus nuclear factor erythroid 2-related factor 2ghrelin/growth hormone secretagogue receptor 1a signaling by Yueju pill confers cardioprotective and antidepressant effects.J Tradit Chin Med | Other paper | 2026 |
| The Ghrelin/GHSR-1a Axis Attenuates Preeclampsia-like Features with Decidual Macrophage Reprogramming and Improved Placental Remodeling.Biomolecules | Other paper | 2026 |
| Growth Hormone-Releasing Peptide-6 (GHRP-6) Ameliorates Post-Infarct Ventricular Remodeling and Systolic Dysfunction in a Model of Permanent Coronary Ligation.Pharmaceuticals (Basel) | Other paper | 2026 |
| Growth hormone releasing peptide-6 (GHRP-6) ameliorates acute lung injury and its subsequent evolvement to interstitial fibrosis.Int Immunopharmacol | Other paper | 2026 |
| Growth hormone-releasing peptide 6 (GHRP-6) hydrogel for acute kidney injury therapy via metabolic regulation.J Nanobiotechnology | Other paper | 2025 |
| Aza-Isotryptophan: Synthesis, Pictet-Spengler Chemistry, Incorporation and Conformational Analysis in Peptides, and Activity in Modulators of the Cluster of Differentiation-36 Receptor.J Med Chem | Other paper | 2025 |
| Assessing The Effectiveness of Growth Hormone Releasing Protein-6 in Improving Human Oocyte Maturation and Meiotic Progression in In Vitro Maturation Culture Media.Int J Fertil Steril | Other paper | 2025 |
| The Ghrelin Analog GHRP-6, Delivered Through Aquafeeds, Modulates the Endocrine and Immune Responses of Sparus aurata Following IFA Treatment.Biology (Basel) | Other paper | 2025 |
| Ghrelin promotes neurologic recovery and neurogenesis in the chronic phase after experimental stroke.Neurol Res Pract | Other paper | 2025 |
| Changes in Locomotor Activity Observed During Acute Nicotine Withdrawal Can Be Attenuated by Ghrelin and GHRP-6 in Rats.Biomedicines | Other paper | 2025 |
| Novel chimeric peptides based on endomorphins and ghrelin receptor antagonist produced supraspinal antinociceptive effects with reduced acute tolerance in mice.Biochimie | Other paper | 2025 |
| Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis.PLoS Negl Trop Dis | Other paper | 2024 |
| Ghrelin alleviates intestinal ischemia-reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway.FASEB J | Other paper | 2024 |
| Growth hormone releasing peptide-6 (GHRP-6) prevents doxorubicin-induced myocardial and extra-myocardial damages by activating prosurvival mechanisms.Front Pharmacol | Other paper | 2024 |
| Ghrelin regulates the endoplasmic reticulum stress signalling pathway in gestational diabetes mellitus.Biochem Biophys Res Commun | Other paper | 2024 |
| In-house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH-related peptides.Biomed Chromatogr | Other paper | 2023 |
| Ghrelin improves cognition via activation of the cAMP- CREB signalling pathway in depressed male C57BL/6J mice.Int J Neurosci | Other paper | 2023 |
| Desacylghrelin modulates GHS-R1 receptor expression and cell differentiation in placental BeWo cells.Mol Cell Endocrinol | Other paper | 2023 |
| Ghrelin Amplifies the Nicotine-Induced Release of Dopamine in the Bed Nucleus of Stria Terminalis (BNST).Biomedicines | Other paper | 2023 |
| Inhibition of ghrelin activity by the receptor antagonist [D-Lys3]-GHRP-6 enhances hepatic fatty acid oxidation and gluconeogenesis in a growing pig model.Peptides | Other paper | 2023 |
| The effects and mechanisms of ghrelin upon angiogenesis in human coronary artery endothelial cells under hypoxia.Peptides | Other paper | 2023 |
| Ghrelin Downregulates Lipopolysaccharide/ Leptin-Induced MUC5AC Expression in Human Nasal Epithelial Cells.Clin Exp Otorhinolaryngol | Other paper | 2023 |
| Intracerebroventricular injection of ghrelin receptor antagonist alleviated NAFLD via improving hypothalamic insulin resistance.Iran J Basic Med Sci | Other paper | 2022 |
| Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD 1067.Sci Rep | Other paper | 2022 |
| Antagonization of Ghrelin Suppresses Muscle Protein Deposition by Altering Gut Microbiota and Serum Amino Acid Composition in a Pig Model.Biology (Basel) | Other paper | 2022 |
| Enteral nutrition alleviated lipopolysaccharides-induced hypercatabolism through ghrelin/GHS-R1α-POMC.Biochem Biophys Res Commun | Other paper | 2022 |
| Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor.Nat Commun | Other paper | 2021 |
| Ghrelin Affects Gastric Cancer Progression by Activating AMPK Signaling Pathway.Biochem Genet | Other paper | 2021 |
| Ghrelin receptor agonist hexarelin attenuates antinociceptive tolerance to morphine in rats.Can J Physiol Pharmacol | Other paper | 2021 |
| Ghrelin Inhibits Intestinal Epithelial Cell Apoptosis Through the Unfolded Protein Response Pathway in Ulcerative Colitis.Front Pharmacol | Other paper | 2021 |
| Ultra-Fast Computation of Excited-States Spectra for Large Systems: Ultraviolet and Fluorescence Spectra of Proteins.Interdiscip Sci | Other paper | 2021 |
| Mass spectrometric and kinetics characterization of modified species of Growth Hormone Releasing Hexapeptide generated under thermal stress in different pH and buffers.J Pharm Biomed Anal | Other paper | 2021 |
| Ghrelin in the lateral parabrachial nucleus influences the excitability of glucosensing neurons, increases food intake and body weight.Endocr Connect | Other paper | 2020 |
| In silico strategy for detailing the binding modes of a novel family of peptides proven as ghrelin receptor agonists.J Mol Model | Other paper | 2020 |
| Fully automated dried blood spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS.Anal Bioanal Chem | Other paper | 2020 |
| Ghrelin up-regulates cartilage-specific genes via the ERK/STAT3 pathway in chondrocytes of patients with adolescent idiopathic scoliosis.Biochem Biophys Res Commun | Other paper | 2019 |
| Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE.Free Radic Biol Med | Other paper | 2019 |
| Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway.Anal Cell Pathol (Amst) | Other paper | 2019 |
| Inhibitor of ghrelin receptor reverses gefitinib resistance in lung cancer.Hum Cell | Other paper | 2019 |
| Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6.Endocrine | Other paper | 2019 |
| Characterization of a third ghrelin receptor, GHS-R3a, in channel catfish reveals novel expression patterns and a high affinity for homologous ligand.Comp Biochem Physiol A Mol Integr Physiol | Other paper | 2019 |
| Effects of Ghrelin on the Apoptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocyte MH7A Cells.Biol Pharm Bull | Other paper | 2019 |
| Glycine-modified growth hormone secretagogues identified in seized doping material.Drug Test Anal | Other paper | 2019 |
| Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists.FASEB J | Other paper | 2019 |
| A Linear Fragment of Unacylated Ghrelin (UAG6-13) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner.Front Endocrinol (Lausanne) | Other paper | 2018 |
| Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism.Front Endocrinol (Lausanne) | Other paper | 2018 |
| Azasulfurylpeptide Modulation of CD36-Mediated Inflammation Without Effect on Neovascularization.Biomedicines | Other paper | 2018 |
| A stable meta-carborane enables the generation of boron-rich peptide agonists targeting the ghrelin receptor.J Pept Sci | Other paper | 2018 |
| Peptidomimetic growth hormone secretagogue derivatives for positron emission tomography imaging of the ghrelin receptor.Eur J Med Chem | Other paper | 2018 |
| Ghrelin Stimulates Endothelial Cells Angiogenesis through Extracellular Regulated Protein Kinases (ERK) Signaling Pathway.Int J Mol Sci | Other paper | 2018 |
| Growth hormone-releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study.Int Wound J | Other paper | 2018 |
| Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via Mediating Ghrelin and GABAA Receptor Signaling Pathway.Front Pharmacol | Other paper | 2018 |
| A polypeptide-mediated synthesis of green fluorescent gold nanoclusters for Fe3+ sensing and bioimaging.J Colloid Interface Sci | Other paper | 2017 |
| Growth Hormone Secretagogue Treatment in Hypogonadal Men Raises Serum Insulin-Like Growth Factor-1 Levels.Am J Mens Health | Other paper | 2017 |
| Azapeptide Synthesis Methods for Expanding Side-Chain Diversity for Biomedical Applications.Acc Chem Res | Other paper | 2017 |
| Diversity-Oriented Synthesis of Cyclic Azapeptides by A3 -Macrocyclization Provides High-Affinity CD36-Modulating Peptidomimetics.Angew Chem Int Ed Engl | Other paper | 2017 |
| Dlitiazem inhibits the oxidative stress induced by angiotensin II through growth hormone secretagogue receptor type 1a in human umbilicus vein endothelial cells.Biomed Pharmacother | Other paper | 2017 |
| Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems.Cell Physiol Biochem | Other paper | 2017 |