5-amino-1MQ
5-amino-1-methylquinolinium · NNMT inhibitor
A small molecule, not a peptide, that blocks a metabolism enzyme (NNMT). There are three scientific papers and no study in people.
This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.
- Type
- Acts on metabolism
- Stage
- Lab and animals only
- Safety
- Not known
- Doping
- May be banned, WADA 2026
- Risk of fakes
- Not known
- Checked
- Not yet
Doping. It is not on the WADA list, but WADA also bans substances that no health authority has approved, so it may be banned.
Safety. Studied in mice. There are three papers and no study in people. Sources: study 1.
Risk of fakes. We found no tests of products sold outside pharmacies.
Is it legal
| Where | Status | Checked | |
|---|---|---|---|
| PL | No approval | The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. Source | Not yet |
| EU | No approval | The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). Source | Not yet |
| US | No approval | The FDA drug register has no such medicine. Source | Not yet |
How much research exists
These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.
What studies show
- DFat loss
Not clear. Weight and fat fell in obese mice. There are three papers and no study in people.
Reported side effects
What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.
Reports to the FDA (USA)
- Reports
- 0
- Of these, serious
- 0
The FDA has no reports. That is not a sign of safety: almost nobody reports substances from outside pharmacies.
Cases described in medical journals
We found no published case of harm.
FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.
Studies we have read
| Studies | Kind of study | Who was studied | People | Duration | Dose as studied | Who paid |
|---|---|---|---|---|---|---|
| Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice. | In animals | mice, Diet-induced obese mice | – | – | – | Unknown |
More papers we found
We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.
Short answers
- Does 5-amino-1MQ work?
- A small molecule, not a peptide, that blocks a metabolism enzyme (NNMT). There are three scientific papers and no study in people. Fat loss: grade D, not clear. Weight and fat fell in obese mice. There are three papers and no study in people.
- Is 5-amino-1MQ legal?
- PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. The FDA drug register has no such medicine.
- Is 5-amino-1MQ banned in sport?
- May be banned, WADA 2026. It is not on the WADA list, but WADA also bans substances that no health authority has approved, so it may be banned.
- Is 5-amino-1MQ safe?
- Not known. Studied in mice. There are three papers and no study in people.