| Efficacy and safety of thymosin α1 combined with chemotherapy for gastric cancer: a systematic review and meta-analysis of randomized controlled trials.Front Immunol | Pooled analysis | 2026 |
| Thymosin-ɑ1 for people with chronic hepatitis B.Cochrane Database Syst Rev | Pooled analysis | 2026 |
| Efficacy of thymosin α1 for sepsis: a systematic review and meta-analysis of randomized controlled trials.Front Cell Infect Microbiol | Pooled analysis | 2025 |
| Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis.Front Immunol | Pooled analysis | 2025 |
| The Effect of Ulinastatin on Sepsis Outcomes: An Umbrella Review of Meta-Analysis.Clin Ther | Pooled analysis | 2025 |
| Thymosin Alpha 1 Plus Routine Treatment for the Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.J Coll Physicians Surg Pak | Pooled analysis | 2024 |
| The efficacy of thymosin alpha-1 therapy in moderate to critical COVID-19 patients: a systematic review, meta-analysis, and meta-regression.Inflammopharmacology | Pooled analysis | 2023 |
| Thymosin alpha1 use in adult COVID-19 patients: A systematic review and meta-analysis on clinical outcomes.Int Immunopharmacol | Pooled analysis | 2023 |
| The clinical efficacy and adverse effects of Entecavir plus Thymosin alpha-1 combination therapy versus Entecavir Monotherapy in HBV-related cirrhosis: a systematic review and meta-analysis.BMC Gastroenterol | Pooled analysis | 2020 |
| Clinical efficacy and safety of synthetic thymic peptides with chemotherapy for non-small cell lung cancer in China: A systematic review and meta-analysis of 27 randomized controlled trials following the PRISMA guidelines.Int Immunopharmacol | Pooled analysis | 2019 |
| Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted.Cochrane Database Syst Rev | Pooled analysis | 2019 |
| Effect of ulinastatin combined with thymosin alpha1 on sepsis: A systematic review and meta-analysis of Chinese and Indian patients.J Crit Care | Pooled analysis | 2017 |
| The efficacy of thymosin α1 as immunomodulatory treatment for sepsis: a systematic review of randomized controlled trials.BMC Infect Dis | Pooled analysis | 2016 |
| Ulinastatin and/or thymosin α1 for severe sepsis: A systematic review and meta-analysis.J Trauma Acute Care Surg | Pooled analysis | 2016 |
| The Efficacy and Immunomodulatory Effects of Ulinastatin and Thymosin α1 for Sepsis: A Systematic Review and Meta-Analysis.Biomed Res Int | Pooled analysis | 2016 |
| Ulinastatin- and thymosin α1-based immunomodulatory strategy for sepsis: A meta-analysis.Int Immunopharmacol | Pooled analysis | 2015 |
| Thymosin alpha1 based immunomodulatory therapy for sepsis: a systematic review and meta-analysis.Int J Infect Dis | Pooled analysis | 2015 |
| Phyllanthus species versus antiviral drugs for chronic hepatitis B virus infection.Cochrane Database Syst Rev | Pooled analysis | 2013 |
| Thymic peptides for treatment of cancer patients.Cochrane Database Syst Rev | Pooled analysis | 2011 |
| [Treatment with interferon and thymosin alpha-1 versus interferon monotherapy for HBeAg positive chronic hepatitis B: a meta-analysis].Zhonghua Gan Zang Bing Za Zhi | Pooled analysis | 2011 |
| Interventions for treating traumatised permanent front teeth: avulsed (knocked out) and replanted.Cochrane Database Syst Rev | Pooled analysis | 2010 |
| [Evaluation of efficacy of thymosin alpha1 in the treatment of sepsis: a systematic review].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Pooled analysis | 2009 |
| Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysis.Antiviral Res | Pooled analysis | 2008 |
| Preliminary results from a phase II trial of spatially fractionated radiotherapy combined with immunotherapy and anti-angiogenic therapy in patients with bulky solid tumors: early evidence of promising efficacy and favorable safety.Radiat Oncol | Random groups | 2026 |
| Thymosin α1 improves the outcomes of patients with hepatitis B virus-related acute-on-chronic liver failure by restoring immune balance.Immunopharmacol Immunotoxicol | Random groups | 2026 |
| The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial.BMJ | Random groups | 2025 |
| A Prospective and Randomized Control Study on Effects of Thymalfasin for Injection on Perioperative Immune Function and Long-term Prognosis of Patients with Colorectal Cancer.Biotechnol Genet Eng Rev | Random groups | 2024 |
| Immune-Enhancing Treatment among Acute Necrotizing Pancreatitis Patients with Metabolic Abnormalities: A Post Hoc Analysis of a Randomized Clinical Trial.Gut Liver | Random groups | 2024 |
| A pilot trial of Thymalfasin (Ta1) to prevent covid-19 infection and morbidities in renal dialysis patients: Preliminary report.Int Immunopharmacol | Random groups | 2023 |
| Value of Thymosin α1 Combined With Blood Purification to Increase Successful Rescues of Shock Patients.Altern Ther Health Med | Random groups | 2022 |
| Safety and efficacy of Thymosin α1 in the treatment of hepatitis B virus-related acute-on-chronic liver failure: a randomized controlled trial.Hepatol Int | Random groups | 2022 |
| Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial.Intensive Care Med | Random groups | 2022 |
| The effect of thymopentin add-on in hepatitis B e antigen positive chronic hepatitis B after virus suppression by peginterferon plus entecavir therapy.Cell Mol Biol (Noisy-le-grand) | Random groups | 2019 |
| Combination of entecavir with thymosin alpha-1 in HBV-related compensated cirrhosis: a prospective multicenter randomized open-label study.Expert Opin Biol Ther | Random groups | 2018 |
| [Prevention Effect of Thymosin-alpha1 Aganist Early Ventilator-associated Pneumonia in Patients with Mechanical Ventilation].Sichuan Da Xue Xue Bao Yi Xue Ban | Random groups | 2015 |
| [Effect of Acupuncture on Prognosis and Immune Function of Sepsis Patients].Zhongguo Zhong Xi Yi Jie He Za Zhi | Random groups | 2015 |
| Thymosin α1 plus routine treatment inhibit inflammatory reaction and improve the quality of life in AECOPD patients.Immunopharmacol Immunotoxicol | Random groups | 2015 |
| A multicenter, randomized, observation-controlled clinical trial to evaluate the efficacy and safety of thymalfasin adjuvant therapy in patients with HBV-related HCC after curative resection - first announcement of the protocol.Expert Opin Biol Ther | Random groups | 2015 |
| The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial.Crit Care | Random groups | 2013 |
| Efficacy of thymosin α-1 plus peginterferon α-2a combination therapy compared with peginterferon α-2a monotherapy in HBeAg-positive chronic hepatitis B: a prospective, multicenter, randomized, open-label study.Scand J Gastroenterol | Random groups | 2012 |
| Thymosin alpha-1 with peginterferon alfa-2a/ribavirin for chronic hepatitis C not responsive to IFN/ribavirin: an adjuvant role?J Viral Hepat | Random groups | 2012 |
| Thymosin alpha 1 is associated with improved cellular immunity and reduced infection rate in severe acute pancreatitis patients in a double-blind randomized control study.Inflammation | Random groups | 2011 |
| Large randomized study of thymosin alpha 1, interferon alfa, or both in combination with dacarbazine in patients with metastatic melanoma.J Clin Oncol | Random groups | 2010 |
| Effect of thymosin-α(1) on T-helper 1 cell and T-helper 2 cell cytokine synthesis in patients with hepatitis B virus e antigen-positive chronic hepatitis B.J Int Med Res | Random groups | 2010 |
| [Immune and inflammation confusion in severe sepsis and effects of bi-immunomodulation therapy: a prospective, randomized, controlled clinical trial].Zhonghua Yi Xue Za Zhi | Random groups | 2009 |
| Treatment of patients with severe sepsis using ulinastatin and thymosin alpha1: a prospective, randomized, controlled pilot study.Chin Med J (Engl) | Random groups | 2009 |
| [Clinical effects of ulinastatin and thymosin alpha1 on immune-modulation in septic patients].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Random groups | 2009 |
| [Effect of continuous blood purification and thymosin alpha1 on the cellular immunity in patients with severe sepsis: a prospective, randomized, controlled clinical trial].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Random groups | 2009 |
| A new immunomodulatory therapy for severe sepsis: Ulinastatin Plus Thymosin {alpha} 1.J Intensive Care Med | Random groups | 2009 |
| Thymosin alpha1- and ulinastatin-based immunomodulatory strategy for sepsis arising from intra-abdominal infection due to carbapenem-resistant bacteria.J Infect Dis | Random groups | 2008 |
| [The prophylactic effect of thymosin alpha 1 on the acute exacerbation of chronic obstructive pulmonary disease].Sichuan Da Xue Xue Bao Yi Xue Ban | Random groups | 2008 |
| Thymosin alpha 1 provides short-term and long-term benefits in the reimplantation of avulsed teeth: a double-blind randomized control pilot study.Am J Emerg Med | Random groups | 2008 |
| Combination therapy of thymosin alpha-1 and lamivudine for HBeAg positive chronic hepatitis B: A prospective randomized, comparative pilot study.J Gastroenterol Hepatol | Random groups | 2008 |
| Thymosin alpha 1 as an adjunct to influenza vaccination in the elderly: rationale and trial summaries.Ann N Y Acad Sci | Random groups | 2007 |
| [Effects of thymosin-alpha1 on cell immunity function in patients with septic shock].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Random groups | 2007 |
| [Clinical trial with a new immunomodulatory strategy: treatment of severe sepsis with Ulinastatin and Maipuxin].Zhonghua Yi Xue Za Zhi | Random groups | 2007 |
| Hepatitis B virus genotype B is associated with better response to thymosin alpha1 therapy than genotype C.J Viral Hepat | Random groups | 2006 |
| Efficacy of thymosin alpha-1 and interferon alpha in treatment of chronic viral hepatitis B: a randomized controlled study.World J Gastroenterol | Random groups | 2006 |
| [Clinical study and long-term evaluation of immunomodulation therapy on trauma, severe sepsis and multiple organ dysfunction syndrome patients].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Random groups | 2006 |
| A randomized, placebo-controlled trial of thymosin-alpha1 and lymphoblastoid interferon for HBeAg-positive chronic hepatitis B.Antivir Ther | Random groups | 2006 |
| [Prevention and management of lung infections with thymosin alpha1 in critical patients with tracheotomy].Nan Fang Yi Ke Da Xue Xue Bao | Random groups | 2006 |
| [Antiviral therapy of chronic hepatitis B patients resistant to lamivudine].Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | Random groups | 2005 |
| The efficacy and safety of thymosin alpha-1 in Japanese patients with chronic hepatitis B; results from a randomized clinical trial.J Viral Hepat | Random groups | 2005 |
| [Anti-viral therapy using lamivudine and thymosin is helpful to prevent recurrence in hepatocellular carcinoma with coexisting active hepatitis B].Zhonghua Zhong Liu Za Zhi | Random groups | 2005 |
| A randomized, controlled, clinical study of thymosin alpha-1 versus interferon-alpha in [corrected] patients with chronic hepatitis B lacking HBeAg in China [corrected].J Chin Med Assoc | Random groups | 2005 |
| Combination therapy of thymalfasin (thymosin-alpha 1) and peginterferon alfa-2a in patients with chronic hepatitis C virus infection who are non-responders to standard treatment.J Gastroenterol Hepatol | Random groups | 2004 |
| Combination transcatheter hepatic arterial chemoembolization with thymosin alpha1 on recurrence prevention of hepatocellular carcinoma.Hepatogastroenterology | Random groups | 2004 |
| [Transcatheter hepatic arterial chemoembolization and thymosin alpha1 in postoperative treatment of hepatocellular carcinoma].Zhonghua Zhong Liu Za Zhi | Random groups | 2004 |
| Thymalfasin for the treatment of chronic hepatitis B.Expert Rev Anti Infect Ther | Random groups | 2004 |
| Thymosin-alpha 1 plus interferon-alpha for naive patients with chronic hepatitis C: results of a randomized controlled pilot trial.J Viral Hepat | Random groups | 2004 |
| A pilot study of the safety and efficacy of thymosin alpha 1 in augmenting immune reconstitution in HIV-infected patients with low CD4 counts taking highly active antiretroviral therapy.Clin Exp Immunol | Random groups | 2003 |
| A pilot study of thymosin alpha1 therapy for chronic hepatitis B patients.Intern Med | Random groups | 2003 |
| A randomized, controlled study of thymosin-alpha1 therapy in patients with anti-HBe, HBV-DNA-positive chronic hepatitis B.Dig Dis Sci | Random groups | 2000 |
| Thymosin alpha1 treatment of chronic hepatitis B: results of a phase III multicentre, randomized, double-blind and placebo-controlled study.J Viral Hepat | Random groups | 1999 |
| Pharmacokinetics of thymosin alpha1 after subcutaneous injection of three different formulations in healthy volunteers.Int J Clin Pharmacol Ther | Random groups | 1999 |
| Interferon and thymosin combination therapy in naive patients with chronic hepatitis C: preliminary results.Liver | Random groups | 1998 |
| Efficacy of thymosin alpha1 in patients with chronic hepatitis B: a randomized, controlled trial.Hepatology | Random groups | 1998 |
| Combination therapy with thymosin alpha1 and interferon for the treatment of chronic hepatitis C infection: a randomized, placebo-controlled double-blind trial.Hepatology | Random groups | 1998 |
| A randomized controlled trial of thymosin-alpha1 versus interferon alfa treatment in patients with hepatitis B e antigen antibody--and hepatitis B virus DNA--positive chronic hepatitis B.Hepatology | Random groups | 1996 |
| A pilot study of thymosin-alpha 1 therapy for chronic hepatitis D.J Clin Gastroenterol | Random groups | 1996 |
| A double-blind, placebo-controlled, pilot trial of thymosin alpha 1 for the treatment of chronic hepatitis C.Liver | Random groups | 1996 |
| Combined treatment with thymosin-alpha1 and low-dose interferon-alpha after ifosfamide in non-small cell lung cancer: a phase-II controlled trial.Anticancer Res | Random groups | 1996 |
| Combination treatment with zidovudine, thymosin alpha 1 and interferon-alpha in human immunodeficiency virus infection.Int J Clin Lab Res | Random groups | 1994 |
| Thymosin treatment of chronic hepatitis B: a placebo-controlled pilot trial.Hepatology | Random groups | 1991 |
| Augmentation of influenza antibody response in elderly men by thymosin alpha one. A double-blind placebo-controlled clinical study.J Am Geriatr Soc | Random groups | 1989 |
| A randomized trial to evaluate the immunorestorative properties of synthetic thymosin-alpha 1 in patients with lung cancer.J Biol Response Mod | Random groups | 1985 |
| T-cell abnormalities after mediastinal irradiation for lung cancer. The in vitro influence of synthetic thymosin alpha-1.Cancer | Random groups | 1985 |
| Neoadjuvant immunochemotherapy plus thymalfasin in locally advanced gastric cancer: a prospective clinical trial.BMC Med | No random groups | 2026 |
| Hypofractionated radiotherapy combined with a PD-1 inhibitor, granulocyte macrophage-colony stimulating factor, and thymosin-α1 in advanced metastatic solid tumors: a multicenter Phase II clinical trial.Cancer Immunol Immunother | No random groups | 2025 |
| Efficacy of Thymosin α1 in Management of Radiation Pneumonitis in Patients With Locally Advanced Non-Small Cell Lung Cancer Treated With Concurrent Chemoradiotherapy: A Phase 2 Clinical Trial (GASTO-1043).Int J Radiat Oncol Biol Phys | No random groups | 2022 |
| Hypofractionated Radiation Therapy Combined With Weekly Chemotherapy in Patients With Unresectable or Recurrent Thymic Epithelial Tumor: A Prospective, Single-Arm Phase 2 Study (GASTO-1042).Int J Radiat Oncol Biol Phys | No random groups | 2022 |
| The Effect of Recombinant Human Interferon Alpha Nasal Drops to Prevent COVID-19 Pneumonia for Medical Staff in an Epidemic Area.Curr Top Med Chem | No random groups | 2021 |
| [Effect of transcatheter arterial chemoembolization combined with thymosin alpha 1 on the autophagy of immune cells from advanced hepatocellular carcinoma].Zhonghua Yi Xue Za Zhi | No random groups | 2017 |
| Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection.PLoS One | No random groups | 2016 |
| Efficacy of triple therapy with thymalfasin, peginterferon alpha-2a, and ribavirin for the treatment of hispanic chronic HCV nonresponders.Ann Hepatol | No random groups | 2008 |
| [Combination therapy of thymosin alpha1 and high dose dexamethasone in patients with chronic idiopathic thrombocytopenic purpura].Zhonghua Nei Ke Za Zhi | No random groups | 2007 |
| [A clinical study of thymosin alpha1 as an auxiliary in treating spontaneous peritonitis in patients with liver cirrhosis].Zhonghua Gan Zang Bing Za Zhi | No random groups | 2007 |
| Antiviral therapy using lamivudine and thymosin alpha1 for hepatocellular carcinoma coexisting with chronic hepatitis B infection.Hepatogastroenterology | No random groups | 2006 |
| Combination therapy of thymalfasin (thymosin-alpha 1) and peginterferon alfa-2a in patients with chronic hepatitis C virus infection who are non-responders to standard treatment.J Gastroenterol Hepatol | No random groups | 2004 |
| Triple combination of thymalfasin, peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior interferon and ribavirin treatment: 24-week interim results of a pilot study.J Gastroenterol Hepatol | No random groups | 2004 |
| [Clinical trial of sequential antiviral therapy for patients with chronic hepatitis B in China].Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | No random groups | 2004 |
| Long-term outcomes of thymosin-alpha 1 and interferon alpha-2b combination therapy in patients with hepatitis B e antigen (HBeAg) negative chronic hepatitis B.J Pharm Sci | No random groups | 2003 |
| Thymosin-alpha1 and famciclovir combination therapy activates T-cell response in patients with chronic hepatitis B virus infection in immune-tolerant phase.J Viral Hepat | No random groups | 2002 |
| Thymosin alpha in the treatment of chronic hepatitis B: an uncontrolled open-label trial.Indian J Gastroenterol | No random groups | 2002 |
| The combined treatment of interferon alpha-2a and thymosin alpha 1 for chronic hepatitis C: the 48 weeks end of treatment results.J Med Assoc Thai | No random groups | 2001 |
| Combined treatment with thymosin-alpha1 and low dose interferon-alpha after dacarbazine in advanced melanoma.Melanoma Res | No random groups | 2000 |
| Melatonin is responsible for the nocturnal increase observed in serum and thymus of thymosin alpha1 and thymulin concentrations: observations in rats and humans.J Neuroimmunol | No random groups | 2000 |
| Combination low-dose lymphoblastoid interferon and thymosin alpha 1 therapy in the treatment of chronic hepatitis B.J Viral Hepat | No random groups | 1996 |
| Polyethylene glycol-modified interleukin-2 and thymosin alpha 1 in human immunodeficiency virus type 1 infection.J Infect Dis | No random groups | 1996 |
| Sequential chemoimmunotherapy for advanced non-small cell lung cancer using cisplatin, etoposide, thymosin-alpha 1 and interferon-alpha 2a.Eur J Cancer | No random groups | 1995 |
| Treatment with thymosin alpha-1 increases fertilizing capacity of sperm of infertile men: a multicenter trial.Arch Androl | No random groups | 1995 |
| Biochemotherapy with thymosin alpha 1, interleukin-2 and dacarbazine in patients with metastatic melanoma: clinical and immunological effects.Ann Oncol | No random groups | 1994 |
| Thymosin in the early diagnosis and treatment of high risk homosexuals and hemophiliacs with AIDS-like immune dysfunction.Ann N Y Acad Sci | No random groups | 1984 |
| Thymosins: structure, function and therapeutic applications.Thymus | No random groups | 1984 |
| Thymalfasin, a promising adjuvant therapy in small hepatocellular carcinoma after liver resection.Medicine (Baltimore) | Group followed over time | 2017 |
| PRaG5.0 combined with chemotherapy and sequential chemoimmunotherapy for massive SMARCA4-deficient undifferentiated tumor of the cervix: case report.Front Immunol | Case reports | 2026 |
| A case report of successful combined intra-arterial immunotherapy and cytokine genetic therapy treatment in a patient with recurrent glioblastoma.Chin Clin Oncol | Case reports | 2024 |
| PD-1 inhibitor combined with SBRT, GM-CSF, and thymosin alpha-1 in metastatic breast cancer: A case report and literature review.Medicine (Baltimore) | Case reports | 2024 |
| Palliative care and Chinese medicine in a centenarian with primary hepatocellular carcinoma and 27-month follow-up: A case report.Heliyon | Case reports | 2023 |
| Long-term asymptomatic SARS-CoV-2 infection associated with deficiency on multiple immune cells.Biosaf Health | Case reports | 2022 |
| Postpartum extracorporeal membrane oxygenation of a woman with COVID-19-related acute respiratory distress syndrome: A case report.Medicine (Baltimore) | Case reports | 2021 |
| Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells: A case report.Medicine (Baltimore) | Case reports | 2020 |
| Severe Gastric Mycormycosis Infection Followed by Cytomegalovirus Pneumonia in a Renal Transplant Recipient: A Case Report and Concise Review of the Literature.Transplant Proc | Case reports | 2019 |
| Chronic active EBV infection associated with NK cell lymphoma and hemophagocytic lymphohistiocytosis in a 27-year-old woman: A case report.Medicine (Baltimore) | Case reports | 2019 |
| Stage IV Wilms Tumor Treated by Korean Medicine, Hyperthermia and Thymosin-α1: A Case Report.Case Rep Oncol | Case reports | 2016 |
| [The therapeutic effect of high flow nasal cannula oxygen therapy for the first imported case of Middle East respiratory syndrome to China].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | Case reports | 2015 |
| [Clinical analysis of the first patient with imported Middle East respiratory syndrome in China].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | Case reports | 2015 |
| The role of Tα1 on the infective patients after hematopoietic stem cell transplantation.Int J Hematol | Case reports | 2013 |
| [Clinicopathological characterization of prostatic small cell carcinoma: a case report and review of the literature].Zhonghua Nan Ke Xue | Case reports | 2009 |
| [Clinical investigation of outbreak of nosocomial severe acute respiratory syndrome].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | Case reports | 2003 |
| Chronic hepatitis B: current and future treatment options.Pharmacotherapy | Case reports | 2002 |
| Emergence of an S gene mutant during thymosin alpha1 therapy in a patient with chronic hepatitis B.J Infect Dis | Case reports | 1998 |
| Thymic carcinoma of the thyroid.Pathol Int | Case reports | 1996 |
| Malignant thymoma associated with T-cell lymphocytosis. A case report with immunophenotypic and gene rearrangement analysis.Arch Pathol Lab Med | Case reports | 1993 |
| Bone marrow transplantation in DiGeorge syndrome.J Pediatr | Case reports | 1987 |
| Intestinal lymphangiectasia and thymic hypoplasia.Clin Exp Immunol | Case reports | 1985 |
| Pure RBC aplasia and myasthenia gravis. Coexistence of two diseases associated with thymoma.Arch Intern Med | Case reports | 1983 |
| Thymosin α-1 in cancer therapy: Immunomodulatory mechanisms, clinical applications, and translational perspectives.Eur J Pharmacol | Review of studies | 2026 |
| Clinical Applications and Evidence Landscape of Thymosin Alpha 1 as an Immunomodulatory Adjunct in Cancer Care: A Scoping Review.Pharmaceuticals (Basel) | Review of studies | 2026 |
| Thymosin α1 combined with immune checkpoint inhibitors: synergistic remodeling of the tumor immune microenvironment to enhance clinical efficacy and safety.Front Immunol | Review of studies | 2026 |
| Comparative efficacy and safety of immunomodulatory therapies for sepsis: a systematic review and network meta-analysis.Front Med (Lausanne) | Review of studies | 2026 |
| Peptide Therapies in Thyroid Health: Emerging Applications in Endocrine and Immune Modulation.Integr Med (Encinitas) | Review of studies | 2026 |
| Drug Repurposing in Oncology: A Strategic Pathway to Unlocking New Therapeutic Potential.Ther Innov Regul Sci | Review of studies | 2026 |
| Aging and Thymosin Alpha-1.Int J Mol Sci | Review of studies | 2025 |
| T-cell immunobiology and cytokine storm of COVID-19.Prog Mol Biol Transl Sci | Review of studies | 2025 |
| Phenotypic drug discovery: a case for thymosin alpha-1.Front Med (Lausanne) | Review of studies | 2024 |
| Comprehensive Review of the Safety and Efficacy of Thymosin Alpha 1 in Human Clinical Trials.Altern Ther Health Med | Review of studies | 2024 |
| Therapeutic applications of thymosin peptides: a patent landscape 2018-present.Expert Opin Ther Pat | Review of studies | 2023 |
| Repurposing drugs for solid tumor treatment: focus on immune checkpoint inhibitors.Cancer Biol Med | Review of studies | 2023 |
| Mechanism and clinical application of thymosin in the treatment of lung cancer.Front Immunol | Review of studies | 2023 |
| Thymosin α1 and Its Role in Viral Infectious Diseases: The Mechanism and Clinical Application.Molecules | Review of studies | 2023 |
| COVID-19 and beyond: Reassessing the role of thymosin alpha1 in lung infections.Int Immunopharmacol | Review of studies | 2023 |
| Theory and reality of antivirals against SARS-CoV-2.World J Clin Cases | Review of studies | 2021 |
| Immunomodulatory agents as potential therapeutic or preventive strategies for COVID-19.Eur Rev Med Pharmacol Sci | Review of studies | 2021 |
| The right immune-modulation at the right time: thymosin α1 for prevention of severe COVID-19 in cancer patients.Future Oncol | Review of studies | 2021 |
| T cell immunobiology and cytokine storm of COVID-19.Scand J Immunol | Review of studies | 2021 |
| COVID-19: Imbalanced Immune Responses and Potential Immunotherapies.Front Immunol | Review of studies | 2020 |
| Thymosin alpha 1: A comprehensive review of the literature.World J Virol | Review of studies | 2020 |
| Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin.Vaccines (Basel) | Review of studies | 2020 |
| Pharmacological development of the potential adjuvant therapeutic agents against coronavirus disease 2019.J Chin Med Assoc | Review of studies | 2020 |
| Pharmacological and Genomic Approaches in Management of Cystic Fibrosis.Crit Rev Eukaryot Gene Expr | Review of studies | 2020 |
| A Reappraisal of Thymosin Alpha1 in Cancer Therapy.Front Oncol | Review of studies | 2019 |
| Thymosins in multiple sclerosis and its experimental models: moving from basic to clinical application.Mult Scler Relat Disord | Review of studies | 2019 |
| Cellular proteostasis: a new twist in the action of thymosin α1.Expert Opin Biol Ther | Review of studies | 2018 |
| Thymosin alpha 1 treatment for patients with sepsis.Expert Opin Biol Ther | Review of studies | 2018 |
| Unmet needs in cystic fibrosis.Expert Opin Biol Ther | Review of studies | 2018 |
| Serum thymosin alpha 1 levels in normal and pathological conditions.Expert Opin Biol Ther | Review of studies | 2018 |
| Potential mechanism of thymosin-α1-membrane interactions leading to pleiotropy: experimental evidence and hypotheses.Expert Opin Biol Ther | Review of studies | 2018 |
| The effect of thymosin α1 for prevention of infection in patients with severe acute pancreatitis.Expert Opin Biol Ther | Review of studies | 2018 |
| Immunotherapy for hepatitis B in the direct acting antiviral era: Reevaluating the thymosin α1 efficacy trials in the light of a combination therapy approach.J Viral Hepat | Review of studies | 2018 |
| Thymosin alpha 1 and HIV-1: recent advances and future perspectives.Future Microbiol | Review of studies | 2017 |
| Immune Modulation with Thymosin Alpha 1 Treatment.Vitam Horm | Review of studies | 2016 |
| Phosphorylation of Prothymosin α. An Approach to Its Biological Significance.Vitam Horm | Review of studies | 2016 |
| Structures of Thymosin Proteins.Vitam Horm | Review of studies | 2016 |
| Historical review on thymosin α1 in oncology: preclinical and clinical experiences.Expert Opin Biol Ther | Review of studies | 2015 |
| Immunomodulatory adjuvant therapy in severe community-acquired pneumonia.Expert Rev Respir Med | Review of studies | 2014 |
| Lung cancer chemotherapy, new treatment and related patents.Recent Pat Anticancer Drug Discov | Review of studies | 2014 |
| Thymosin α1 as a stimulatory agent of innate cell-mediated immune response.Ann N Y Acad Sci | Review of studies | 2012 |
| Thymosin α1 in melanoma: from the clinical trial setting to the daily practice and beyond.Ann N Y Acad Sci | Review of studies | 2012 |
| Thymosin α1 and cancer: action on immune effector and tumor target cells.Ann N Y Acad Sci | Review of studies | 2012 |
| Jack of all trades: thymosin α1 and its pleiotropy.Ann N Y Acad Sci | Review of studies | 2012 |
| Prothymosin alpha: a ubiquitous polypeptide with potential use in cancer diagnosis and therapy.Cancer Immunol Immunother | Review of studies | 2012 |
| Medical management of chronic liver diseases in children (part I): focus on curable or potentially curable diseases.Paediatr Drugs | Review of studies | 2011 |
| Utility of thymosin alpha-1 (Zadaxin) as a co-adjuvant in influenza vaccines: a review.J Prev Med Hyg | Review of studies | 2011 |
| Preclinical studies with IRX-2 and thymosin alpha1 in combination therapy.Ann N Y Acad Sci | Review of studies | 2010 |
| Thymosin alpha1 to harness immunity to pathogens after haploidentical hematopoietic transplantation.Ann N Y Acad Sci | Review of studies | 2010 |
| Thymalfasin in the treatment of hepatitis B and C.Ann N Y Acad Sci | Review of studies | 2010 |
| Thymosin alpha 1 for treatment of hepatitis C virus: promise and proof.Ann N Y Acad Sci | Review of studies | 2010 |
| Thymosin alpha 1: past clinical experience and future promise.Ann N Y Acad Sci | Review of studies | 2010 |
| Transcription profile of human lymphocytes following in vitro treatment with thymosin alpha-1.Ann N Y Acad Sci | Review of studies | 2010 |
| Thymosin alpha1: the regulator of regulators?Ann N Y Acad Sci | Review of studies | 2010 |
| Treatment with lamivudine versus lamivudine and thymosin alpha-1 for e antigen-positive chronic hepatitis B patients: a meta-analysis.Virol J | Review of studies | 2009 |
| From lab to bedside: emerging clinical applications of thymosin alpha 1.Expert Opin Biol Ther | Review of studies | 2009 |
| Thymosin alpha1: a promising molecule for important clinical applications.Med Arh | Review of studies | 2009 |
| Neuropeptides and thymic hormones in the Xenopus thymus.Front Biosci (Landmark Ed) | Review of studies | 2009 |
| Provision of antifungal immunity and concomitant alloantigen tolerization by conditioned dendritic cells in experimental hematopoietic transplantation.Blood Cells Mol Dis | Review of studies | 2008 |
| Thymosin alpha1: an endogenous regulator of inflammation, immunity, and tolerance.Ann N Y Acad Sci | Review of studies | 2007 |
| beta-Thymosins.Ann N Y Acad Sci | Review of studies | 2007 |
| Thymic reticulo-epithelial cells: key cells of neuroendocrine regulation.Expert Opin Biol Ther | Review of studies | 2007 |
| Thymalfasin for the treatment of chronic hepatitis C infection.Expert Rev Anti Infect Ther | Review of studies | 2005 |
| Thymalfasin (thymosin-alpha 1) therapy in patients with chronic hepatitis B.J Gastroenterol Hepatol | Review of studies | 2004 |
| Thymalfasin: an immune system enhancer for the treatment of liver disease.J Gastroenterol Hepatol | Review of studies | 2004 |
| Thymalfasin (thymosin-alpha 1) therapy in patients with chronic hepatitis B.J Gastroenterol Hepatol | Review of studies | 2004 |
| Thymalfasin: an immune system enhancer for the treatment of liver disease.J Gastroenterol Hepatol | Review of studies | 2004 |
| Past, present, and future hepatitis C treatments.Semin Liver Dis | Review of studies | 2004 |
| Current therapy and new molecular approaches to antiviral treatment and prevention of hepatitis C.Rev Med Virol | Review of studies | 2003 |
| Thymosin in the treatment of HBeAg-negative chronic hepatitis B.Med Sci Monit | Review of studies | 2003 |
| T cell targeted immune enhancement yields effective T cell adjuvants.Int Immunopharmacol | Review of studies | 2003 |
| Combination therapy in the treatment of chronic viral hepatitis and prevention of hepatocellular carcinoma.Int Immunopharmacol | Review of studies | 2003 |
| Thymosin alpha(1) in combination with cytokines and chemotherapy for the treatment of cancer.Int Immunopharmacol | Review of studies | 2003 |
| Immunodeficiency and cancer: prospects for correction.Int Immunopharmacol | Review of studies | 2003 |
| A novel porcine interleukin-2-interferon-α-thymosin α1 tripartite fusion protein confers antiviral activity against pseudorabies virus.Vet Microbiol | In animals | 2026 |
| Thymosin α1 alleviates lung injury in sepsis rats via Notch signaling pathway.Panminerva Med | In animals | 2023 |
| Enhanced metabolic activation of and platelet response to clopidogrel in T cell-deficient mice through induction of Cyp2c and Cyp3a and inhibition of Ces1.J Thromb Haemost | In animals | 2023 |
| Immunological effects of heated intraperitoneal chemotherapy can be augmented by thymosin α1.Int Immunopharmacol | In animals | 2023 |
| [Structural changes and functional evaluation of the thymus in aging mouse induced by D-galactose].Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | In animals | 2022 |
| Thymosin alpha 1 as an adjuvant to hyperthermic intraperitoneal chemotherapy in an experimental model of peritoneal metastases from colonic carcinoma.Int Immunopharmacol | In animals | 2022 |
| Highly oxygenated isoryanodane diterpenoids from the leaves of Cinnamomum cassia and their immunomodulatory activities.Phytochemistry | In animals | 2022 |
| Hormonal Regulation of the MHC Class I Gene in Thyroid Cells: Role of the Promoter "Tissue-Specific" Region.Front Endocrinol (Lausanne) | In animals | 2021 |
| Zuogui Wan alleviated maternal kidney-yin deficiency-induced thymic epithelial cell dysfunction in newborn rats through Wnt/β-catenin signaling pathway.J Ethnopharmacol | In animals | 2021 |
| DNA Dendrons as Agents for Intracellular Delivery.J Am Chem Soc | In animals | 2021 |
| PASylated Thymosin α1: A Long-Acting Immunostimulatory Peptide for Applications in Oncology and Virology.Int J Mol Sci | In animals | 2020 |
| Improvement in cognitive dysfunction following blast induced traumatic brain injury by thymosin α1 in rats: Involvement of inhibition of tau phosphorylation at the Thr205 epitope.Brain Res | In animals | 2020 |
| Thymosin α1 protects from CTLA-4 intestinal immunopathology.Life Sci Alliance | In animals | 2020 |
| Immunopotentiator thymosin alpha-1 attenuates inflammatory pain by modulating the Wnt3a/β-catenin pathway in spinal cord.Neuroreport | In animals | 2020 |
| Fusion of thymosin alpha 1 with mutant IgG1 CH3 prolongs half-life and enhances antitumor effects in vivo.Int Immunopharmacol | In animals | 2019 |
| Thymosin Alpha-1 Inhibits Complete Freund's Adjuvant-Induced Pain and Production of Microglia-Mediated Pro-inflammatory Cytokines in Spinal Cord.Neurosci Bull | In animals | 2019 |
| Effect of a C-end rule modification on antitumor activity of thymosin α1.Biochimie | In animals | 2018 |
| Gene cloning, expression and immune adjuvant properties of the recombinant fusion peptide Tα1-BLP on avian influenza inactivate virus vaccine.Microb Pathog | In animals | 2018 |
| Effect of Boron on Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Proliferation, and Apoptosis Potential via the Extracellular Signal-Regulated Kinases 1 and 2 Signaling Pathway.J Agric Food Chem | In animals | 2017 |
| Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias.Neurosci Bull | In animals | 2017 |
| Investigation of the immunomodulatory activity of Tricholoma matsutake mycelium in cyclophosphamide-induced immunosuppressed mice.Mol Med Rep | In animals | 2017 |
| [The Effects of Thymosin alpha1 on Immune Function of Mice after Skin Transplantation].Sichuan Da Xue Xue Bao Yi Xue Ban | In animals | 2015 |
| Efficacy of thymosin α1 and interferon α for the treatment of severe acute pancreatitis in a rat model.Mol Med Rep | In animals | 2015 |
| Thymosin α1 promotes the activation of myeloid-derived suppressor cells in a Lewis lung cancer model by upregulating Arginase 1.Biochem Biophys Res Commun | In animals | 2015 |
| [Triplet anti-tumor therapy based on thymosin α-1 attenuates incidence of hepatoma and serum alpha-fetoprotein level in rat hepatoma model].Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | In animals | 2015 |
| Immunogenicity in Swine of Orally Administered Recombinant Lactobacillus plantarum Expressing Classical Swine Fever Virus E2 Protein in Conjunction with Thymosin α-1 as an Adjuvant.Appl Environ Microbiol | In animals | 2015 |
| Evaluation of thymosin α 1 in nonclinical models of the immune-suppressing indications melanoma and sepsis.Expert Opin Biol Ther | In animals | 2015 |
| [Effects of thymosin alpha1 on immune effector molecules of mouse].Sichuan Da Xue Xue Bao Yi Xue Ban | In animals | 2014 |
| Combination therapy with thymosin alpha1 and dexamethasone helps mice survive sepsis.Inflammation | In animals | 2014 |
| The in vivo immunomodulatory and synergistic anti-tumor activity of thymosin α1-thymopentin fusion peptide and its binding to TLR2.Cancer Lett | In animals | 2013 |
| Thymosin α1 continues to show promise as an enhancer for vaccine response.Ann N Y Acad Sci | In animals | 2012 |
| [Ulinastatin combined with thymosin α1 for treatment of severe sepsis: a histopathological observation in rats].Nan Fang Yi Ke Da Xue Xue Bao | In animals | 2012 |
| The use of growth factors to modulate the activities of antigen-specific CD8+ T cells in vitro.J Med Life | In animals | 2011 |
| Thymosin-alpha1 promotes the apoptosis of regulatory T cells and survival rate in septic mice.Front Biosci (Landmark Ed) | In animals | 2011 |
| Thymosin alpha 1: biological activities, applications and genetic engineering production.Peptides | In animals | 2010 |
| In vitro and in vivo study of thymosin alpha1 biodegradable in situ forming poly(lactide-co-glycolide) implants.Int J Pharm | In animals | 2010 |
| [Purification of recombinant proteins with an example of tumor necrosis factor thymosin-alpha1].Prikl Biokhim Mikrobiol | In animals | 2010 |
| Intraperitoneal co-administration of thymosin alpha-1 ameliorates streptozotocin-induced pancreatic lesions and diabetes in C57BL/6 mice.Int J Mol Med | In animals | 2009 |
| Expression of thymosin alpha1-thymopentin fusion peptide in Pichia pastoris and its characterization.Arch Pharm Res | In animals | 2008 |
| Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells.Cell Biol Int | In animals | 2008 |
| Expression and analysis of thymosin alpha1 concatemer in Escherichia coli.Biotechnol Appl Biochem | In animals | 2008 |
| Thymosin alpha 1 improves severe acute pancreatitis in rats via regulation of peripheral T cell number and cytokine serum level.J Gastroenterol Hepatol | In animals | 2007 |
| Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo.Int Immunol | In animals | 2007 |
| Thymosin alpha 1: from bench to bedside.Ann N Y Acad Sci | In animals | 2007 |
| Thymosin alpha1 as a chemopreventive agent in lung and breast cancer.Ann N Y Acad Sci | In animals | 2007 |
| Studies of bioactivity, conformation and pharmacokinetic profiles of site-specific PEGylated thymosin alpha 1 derivatives.Drug Metab Lett | In animals | 2007 |
| Solid-phase synthesis of a peptide derivative of thymosin alpha1 and initial studies on its (99m)Tc-radiolabelling.Chem Biol Drug Des | In animals | 2007 |
| [Preparation and properties of Talpha1 loaded injectable sustained release microspheres].Yao Xue Xue Bao | In animals | 2007 |
| Construction and application of a yeast expression system for thymosin alpha1.Biocell | In animals | 2005 |
| Immunomodulatory function of orally administered thymosin alpha1.J Zhejiang Univ Sci B | In animals | 2005 |
| Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway.EMBO Rep | In animals | 2005 |
| Thymosin alpha 1 attenuates lipid peroxidation and improves fructose-induced steatohepatitis in rats.Clin Biochem | In animals | 2005 |
| [Combination of lamivudine with thymosin alpha1 in treatment of duck hepatitis B].Zhejiang Da Xue Xue Bao Yi Xue Ban | In animals | 2005 |
| Construction and expression of a new fusion protein, thymosin alpha1-cBLyS, E. coli.Biotechnol Lett | In animals | 2005 |
| Antitumor activation of peritoneal macrophages by thymosin alpha-1.Cancer Invest | In animals | 2005 |
| Avian thymic hormone treatment of peripheral blood mononuclear cells from young chicks stimulates acute graft-versus-host reaction in chicken embryos.Dev Comp Immunol | In animals | 2005 |
| [Effect of thymosin alpha1 on immunological function and metabolism in peritoneal sepsis rats].Zhonghua Wai Ke Za Zhi | In animals | 2004 |
| Effect of thymosin alpha 1 on the antitumor activity of tumor-associated macrophage-derived dendritic cells.J Biomed Sci | In animals | 2004 |
| Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling.Blood | In animals | 2004 |
| Thymosin α1-induced secretion of the IL-15/RA complex by THP-1-derived dendritic cells restrains HIV latency in vitro.Virulence | In a lab dish | 2026 |
| Bioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity.Sci Rep | In a lab dish | 2019 |
| Thymosin α-1 does not correct F508del-CFTR in cystic fibrosis airway epithelia.JCI Insight | In a lab dish | 2018 |
| Thymosin alpha1 enhanced cytotoxicity of iNKT cells against colon cancer via upregulating CD1d expression.Cancer Lett | In a lab dish | 2015 |
| The modulation of thymosin alpha 1 in the maturation, differentiation and function of murine bone marrow-derived dendritic cells in the absence or presence of tumor necrosis factor-alpha.Int Immunopharmacol | In a lab dish | 2004 |
| Thymosin alpha1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro.Int J Immunopharmacol | In a lab dish | 2000 |
| Thymosin-alpha1 stimulates maturation of CD34+ stem cells into CD3+4+ cells in an in vitro thymic epithelia organ coculture model.Int J Immunopharmacol | In a lab dish | 1999 |
| [The effect of complete thymic extract on motility and progressive motility of spermatozoa in asthenozoospermia].Srp Arh Celok Lek | In a lab dish | 1996 |
| Thymosin alpha-1 and FA-1 monoclonal antibody affect murine preimplantation embryo development by modulating protein phosphorylation.J Reprod Immunol | In a lab dish | 1995 |
| Effect of thymosin alpha 1 on hypothalamic hormone release.Neuroendocrinology | In a lab dish | 1992 |
| Solid-phase syntheses of two deacetyl-thymosin alpha 1 analogues with substitution at position 21 and their effects on low E-rosette-forming lymphocytes of uremic patients.Biotechnol Ther | In a lab dish | 1992 |
| Synthesis of an immunologically active fragment analog of prothymosin alpha with enhanced enzymatic stability.Chem Pharm Bull (Tokyo) | In a lab dish | 1991 |
| The octapeptide corresponding to the region of the highest homology between alpha-interferon and thymosin-alpha 1 effectively competes with both cytokines for common high-affinity receptors on murine thymocytes.FEBS Lett | In a lab dish | 1991 |
| Thymosin alpha 1 and thymosin beta 4 modulate human colonic lamina propria lymphocyte function.Immunopharmacology | In a lab dish | 1990 |
| Thymosin alpha 1 enhancement of human lymphocyte proliferation is not mediated by prostaglandin E2.Thymus | In a lab dish | 1990 |
| Phytohemagglutin-stimulated human T cell: prothymosin alpha as an accessory signal.J Biol Regul Homeost Agents | In a lab dish | 1990 |
| Thymosin enhances the production of IL-1 alpha by human peripheral blood monocytes.Lymphokine Res | In a lab dish | 1989 |
| Thymosins alpha 1 and beta 4 potentiate the antigen-presenting capacity of macrophages.Immunopharmacology | In a lab dish | 1989 |
| Aspirin and thymosin increase interleukin-2 and interferon-gamma production by human peripheral blood lymphocytes.Immunopharmacology | In a lab dish | 1989 |
| Interaction of thymic peptide thymosin alpha 1 with VIP receptors in rat intestinal epithelial cells: comparison with PHI and secretin.Gen Pharmacol | In a lab dish | 1989 |
| Production of human B and T cell growth factors is enhanced by thymic hormones.Immunopharmacology | In a lab dish | 1988 |
| Encapsulated thymic epithelial cells as a potential treatment for immunodeficiencies.ASAIO Trans | In a lab dish | 1988 |
| MicroELISA detection of thymosin alpha 1 released in thymic organ cultures.J Immunol Methods | In a lab dish | 1988 |
| Micro ELISA for measurement of parathymosin alpha utilizing a monoclonal antibody.Thymus | In a lab dish | 1988 |
| Phase II trial of thymosin fraction 5 and thymosin alpha 1.J Biol Response Mod | In a lab dish | 1987 |
| Immunoregulatory effects of fraction 5 thymus peptides. I. Thymosin alpha 1 enhances while thymosin beta 4 suppresses the human autologous and allogeneic mixed lymphocyte reaction.Immunopharmacology | In a lab dish | 1987 |
| Effect of two thymosin fraction 5 polypeptides on human peripheral blood lymphocytes.Immunopharmacol Immunotoxicol | In a lab dish | 1987 |
| Circulating thymulin and thymosin-alpha 1 activity in pediatric acquired immune deficiency syndrome: in vivo and in vitro studies.J Pediatr | In a lab dish | 1986 |
| Comparison of the effects of thymosin and other thymic factors on modulation of interleukin-2 production.J Biol Response Mod | In a lab dish | 1985 |
| Interleukin-2 and aging: decreased interleukin-2 production in healthy older people does not correlate with reduced helper cell numbers or antibody response to influenza vaccine and is not corrected in vitro by thymosin alpha 1.Immunopharmacology | In a lab dish | 1985 |
| Thymosin Alpha-1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis.Adv Sci (Weinh) | Other paper | 2026 |
| Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells.Cancer Res | Other paper | 2026 |
| A prospective clinical study on the effectiveness of Phellinus igniarius decoction in treating immune dysfunction in colorectal cancer patients following chemfotherapy.J Tradit Complement Med | Other paper | 2026 |
| [Risk factors of death in patients with bloodstream infections in a medical intensive care unit].Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | Other paper | 2026 |
| Thymosin α1 Augments CD8⁺ T-Cell Activation and Reverses Exhaustion In Vitro.Asian Pac J Cancer Prev | Other paper | 2026 |
| IL-15 Plus Thymosin α1 Reduces Senescent Hepatic CD8+ T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression.J Gastroenterol Hepatol | Other paper | 2026 |
| Thymalfasin combined with immune checkpoint inhibitors in the treatment of non-small cell lung cancer: A retrospective study on efficacy, safety, and immunological function.Pak J Med Sci | Other paper | 2026 |
| A multipronged Tα1 reset of CD8+ T cell cytotoxicity against breast cancer.Hum Immunol | Other paper | 2026 |
| A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1.Clin Case Rep | Other paper | 2026 |
| Zerumbone mediated CD1d inhibition suppresses epithelial to mesenchymal transition in triple negative breast cancer.Discov Oncol | Other paper | 2026 |
| Thymosin α1 Combined with PD-1/PD-L1 Inhibitor Plus Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer : A Retrospective Analysis.Cancer Manag Res | Other paper | 2025 |
| Exploiting the potential of in situ forming liquid crystals: development and in vitro performance of long-acting depots for peptide drug thymosin alpha 1 subcutaneous administration.Drug Deliv | Other paper | 2025 |
| Cross-Expression of Thymic and Parathyroid Hormone Receptors Supports the Hypothesis of a Parathyroid-Thymus Port System.Int J Mol Sci | Other paper | 2025 |
| MRAP mediated adipocyte differentiation by thymic mesenchymal stromal cells contributes to thymic involution.Nat Commun | Other paper | 2025 |
| Thymosin α1 Elevates Lymphocyte Counts and Improves Immunoradiotherapy Outcomes in Patients with Advanced Cancer.Cancer Manag Res | Other paper | 2025 |
| Thymosin α1 alleviates pulpitis by inhibiting ferroptosis of dental pulp cells.Int J Oral Sci | Other paper | 2025 |
| Thymosin α1 Combined With 2HRZE/4HR Regimen as a Potential Treatment of Pulmonary Tuberculosis: An Analysis of Immune Function, Pulmonary Function and Inflammatory Response.Br J Hosp Med (Lond) | Other paper | 2025 |
| Expression levels of thymosin α1 in acute myocardial infarction patients and its correlation to cardiac function.Front Cardiovasc Med | Other paper | 2025 |
| The Immunomodulatory Activity of Thymosin Alpha 1 on Tumor Cell Lines and Distinct Immune Cell Subsets.Onco Targets Ther | Other paper | 2025 |
| Interferon-α and thymosin-α1 plus tislelizumab enhance CD8+ T cell cytotoxicity toward pancreatic ductal adenocarcinoma.iScience | Other paper | 2025 |
| A preliminary analysis of integrating thymosin α1 into concurrent chemoradiotherapy and consolidative immunotherapy in unresectable locally advanced non-small cell lung cancer.Transl Lung Cancer Res | Other paper | 2025 |
| The Synergistic and Attenuated Mechanism of Action of the Xihuang Pill in Dual Immunotherapy After Stenting for Advanced Cholangiocarcinoma: A Controlled Clinical Trial.Int J Gen Med | Other paper | 2025 |
| Effect of thymosin α1 on Immune response and organ function in acute aortic dissection surgery: PANDA II trial protocol.Future Cardiol | Other paper | 2025 |
| The efficacy and safety of thymosin alpha-1 combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a retrospective study.Sci Rep | Other paper | 2025 |
| Synergistic effects of recombinant expressed Fowlicidin and Thymosin α1 hybrid peptides in modulating inflammation and infection in avian macrophages.Front Microbiol | Other paper | 2025 |
| Indications for an antidepressive effect of thymosin alpha-1 in a small open-label proof of concept study in common variable immune deficiency patients with depression.Brain Behav Immun Health | Other paper | 2025 |
| Unveiling lymphocyte dynamics: Navigating postoperative immune landscapes in gastric cancer patients undergoing laparoscopic D2 gastrectomy.Int J Immunopathol Pharmacol | Other paper | 2025 |
| Personalized neoantigen hydrogel vaccine combined with PD-1 and CTLA-4 double blockade elicits antitumor response in liver metastases by activating intratumoral CD8+CD69+ T cells.J Immunother Cancer | Other paper | 2024 |
| Effect analysis of entecavir on serum hyaluronic acid, laminin and IV collagen in the treatment of hepatitis B E-antigen-positive chronic hepatitis B.Afr Health Sci | Other paper | 2024 |
| Single-cell RNA sequencing combined with proteomics of infected macrophages reveals prothymosin-α as a target for treatment of apical periodontitis.J Adv Res | Other paper | 2024 |
| Thymosin α1 reverses oncolytic adenovirus-induced M2 polarization of macrophages to improve antitumor immunity and therapeutic efficacy.Cell Rep Med | Other paper | 2024 |
| N-Butylpyrrolidinone is an equally good solvent as N,N-dimethylformamide for microwave assisted solid phase peptide synthesis.J Pept Sci | Other paper | 2024 |
| Effect of thymalfasin on myeloid-derived suppressor cells in patients with non-small cell lung cancer.Am J Transl Res | Other paper | 2024 |
| Thymosin α1 combined with XELOX improves immune function and reduces serum tumor markers in colorectal cancer patients after radical surgery.Open Life Sci | Other paper | 2024 |
| Efficacy of the combination of BRII-196/BRII-198 in the treatment of COVID-19 vaccine breakthrough infections.Am J Transl Res | Other paper | 2024 |
| Evaluation of the efficacy and safety of a precise thymalfasin-regulated PRaG regimen for advanced refractory solid tumours: protocol for the open-label, prospective, multicentre study (PRaG5.0 study).BMJ Open | Other paper | 2024 |
| Robust Chemical Synthesis of "Difficult Peptides" via 2-Hydroxyphenol-pseudoproline (ψ2-hydroxyphenolpro) Modifications.J Org Chem | Other paper | 2024 |
| Enhanced Immunomodulatory Effects of Thymosin-Alpha-1 in Combination with Polyanionic Carbosilane Dendrimers against HCMV Infection.Int J Mol Sci | Other paper | 2024 |
| Role of thymosin α1 in restoring immune response in immunological nonresponders living with HIV.BMC Infect Dis | Other paper | 2024 |
| Immune modulation via dendritic cells by the effect of Thymosin-alpha-1 on immune synapse in HCMV infection.Int Immunopharmacol | Other paper | 2023 |
| Thymosin α1 modulated the immune landscape of COVID-19 patients revealed by single-cell RNA and TCR sequencing.Int Immunopharmacol | Other paper | 2023 |
| Thymalfasin therapy accelerates COVID-19 pneumonia rehabilitation through anti-inflammatory mechanisms.Pneumonia (Nathan) | Other paper | 2023 |
| The use of alpha 1 thymosin as an immunomodulator of the response against SARS-Cov2.Immun Ageing | Other paper | 2023 |
| Zoledronic acid and thymosin α1 elicit antitumor immunity against prostate cancer by enhancing tumor inflammation and cytotoxic T cells.J Immunother Cancer | Other paper | 2023 |
| Reduced numbers of naïve CD4 + T cells and an altered CD4/CD8 balance in depressed common variable immune deficiency (CVID) patients. Is thymosin-α1 a possible treatment?Int Immunopharmacol | Other paper | 2023 |
| Thymosin α1 interacts with Galectin-1 modulating the β-galactosides affinity and inducing alteration in the biological activity.Int Immunopharmacol | Other paper | 2023 |
| Thymosin alpha 1 restores the immune homeostasis in lymphocytes during Post-Acute sequelae of SARS-CoV-2 infection.Int Immunopharmacol | Other paper | 2023 |
| Association between pretreatment lymphocyte count and efficacy of immune-enhancing therapy in acute necrotising pancreatitis: a post-hoc analysis of the multicentre, randomised, placebo-controlled TRACE trial.EClinicalMedicine | Other paper | 2023 |
| Novel evidence of Thymosin α1 immunomodulatory properties in SARS-CoV-2 infection: Effect on innate inflammatory response in a peripheral blood mononuclear cell-based in vitro model.Int Immunopharmacol | Other paper | 2023 |
| Adenovirus infection diagnosed by metagenomic next-generation sequencing after haploidentical hematopoietic stem cell transplantation: A multicenter study in China.Transpl Infect Dis | Other paper | 2023 |
| Thymosin alpha 1 - Reimagine its broader applications in the immuno-oncology era.Int Immunopharmacol | Other paper | 2023 |
| Thymosin α-1 in cancer therapy: Immunoregulation and potential applications.Int Immunopharmacol | Other paper | 2023 |
| Higher plasma levels of thymosin-α1 are associated with a lower waning of humoral response after COVID-19 vaccination: an eight months follow-up study in a nursing home.Immun Ageing | Other paper | 2023 |
| Factors associated with the humoral response after three doses of COVID-19 vaccination in kidney transplant recipients.Front Immunol | Other paper | 2023 |
| Immunological responses of septic rats to combination therapy with thymosin α1 and vitamin C.Open Life Sci | Other paper | 2023 |
| A Pilot Trial of Thymalfasin (Thymosin-α-1) to Treat Hospitalized Patients With Hypoxemia and Lymphocytopenia Due to Coronavirus Disease 2019 Infection.J Infect Dis | Other paper | 2023 |