Graded
The US health department published a draft policy under which it would not act against pharmacies that make BPC-157 on a prescription for a named patient, until the FDA decides by rule. It is still not an approved medicine.
PL

RAD-140

testolone · vosilasarm

A SARM still being studied. No such medicine exists.

This site is for information and education only. It does not promote or encourage the use or purchase of the substances described and is not medical advice. Many are not authorised as medicines and their safety has not been established. We sell nothing and have no ties to sellers. For health decisions, consult a doctor.

Type
SARM
Stage
Still being studied
Safety
Serious warning
Doping
Banned in sport, WADA 2026
Risk of fakes
High
Checked
Not yet

Safety. A case report describes liver damage with blocked bile flow in a 24-year-old man after 5 weeks of use. Sources: study 1.

Risk of fakes. These tests cover products sold as SARMs and do not name RAD-140. Of 44 products, 52% held any SARM and 41% matched the label. Sources: study 1, study 2.

Is it legal

How much research exists

Scientific papers
43
Studies with random groups
0
Registered studies in people
1

Scientific papers per year 2015–2025

These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.

What studies show

  • DMuscle mass

    Conflicting results. Animal studies only. In young rats muscle fibres grew thicker. In female mice strength did not rise after 10 weeks and overall health got worse. The only study in people was in breast cancer and did not measure muscle.

  • DStrength

    No effect in studies. One study in female mice: after 10 weeks strength did not differ from the control group, and the mice were frailer and more likely to die.

Reported side effects

What doctors, patients and companies reported to the US medicines agency (FDA), and single cases described in medical journals. A report says what happened to someone after taking the substance. It does not prove the substance caused it, and it does not say how often it happens. Reports do not change any grade.

Reports to the FDA (USA)

Reports
19
Of these, serious
17
Most often reportedReports
Kidney tissue death from blocked blood5
Spleen tissue death from blocked blood5
Blood clot in an artery4
Blood clot in the aorta3
Liver damage caused by a substance3
Stomach pain2
Blocked bile flow2
High blood pressure2

Serious means the person went to hospital, their life was in danger, they were left with lasting harm, or they died. One report can list several side effects.

All cases in PubMed (9)

FDA reports come from openFDA, cases from a PubMed search. The editors have not read these cases yet. Titles stay in the original language. As of 3 Nov 2026.

Videos on YouTube

Doctor or scientist

SARMs Tier List: Ostarine, RAD-140, MK-677 & LGD Explained by a Doctor

Dr. Alex Tatem · 15 May 2026

A urologist who works on men's health goes through the studies on popular SARMs, MK-677 and cardarine: muscle gain, lower testosterone, the liver, cholesterol, fertility and false labels. According to the description, every SARM gets the lowest rating at the end.

All videos we checked

Studies we have read

StudiesKind of studyWho was studiedPeopleDurationDose as studiedWho paid
Preclinical assessment of the selective androgen receptor modulator RAD140 to increase muscle mass and bone mineral density.Physiol Rep 2025In animalsrats, Young male rats, plantaris muscle overload or none402 wk–Unknown
RAD140 (Testolone) negatively impacts skeletal muscle adaptation, frailty status and mortality risk in female mice.Clin Exp Pharmacol Physiol 2023In animalsmice, Young and adult female mice–10 wk5 mg/kgUnknown

More papers we found

We found these papers automatically in PubMed. The editors have not read them yet, and they do not affect any grade. Titles stay in the original language.

All papers and studies we found (41)

Short answers

Does RAD-140 work?
A SARM still being studied. No such medicine exists. Muscle mass: grade D, conflicting results. Animal studies only. In young rats muscle fibres grew thicker. In female mice strength did not rise after 10 weeks and overall health got worse. The only study in people was in breast cancer and did not measure muscle. Strength: grade D, no effect in studies. One study in female mice: after 10 weeks strength did not differ from the control group, and the mice were frailer and more likely to die.
Is RAD-140 legal?
PL: No approval found. The Polish sanitary inspectorate lists SARMs as not allowed in food supplements. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. The FDA drug register has no such medicine.
Is RAD-140 banned in sport?
Banned in sport, WADA 2026.
Is RAD-140 safe?
Serious warning. A case report describes liver damage with blocked bile flow in a 24-year-old man after 5 weeks of use.

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