| Predictors of Physical and Functional Loss in Advanced-Stage Lung Cancer Patients Receiving Platinum Chemotherapy.J Thorac Oncol | Random groups | 2018 |
| A Phase II Clinical Trial of Pembrolizumab and Enobosarm in Patients with Androgen Receptor-Positive Metastatic Triple-Negative Breast Cancer.Oncologist | No random groups | 2021 |
| Pharmacokinetic drug interactions of the selective androgen receptor modulator GTx-024(Enobosarm) with itraconazole, rifampin, probenecid, celecoxib and rosuvastatin.Invest New Drugs | No random groups | 2016 |
| Evidence of ostarine cross-contamination via sweat in 2 athletes sharing the same neoprene hamstring sleeves. An original situation of drug transfer where the anti-doping rule violation was suspended by the sport authorities.Clin Chim Acta | Case reports | 2024 |
| Liver Injury after Selective Androgen Receptor Modulator Intake: A Case Report and Review of the Literature.Z Gastroenterol | Case reports | 2024 |
| Body fluid contamination in the context of an adverse analytical finding in doping: About a case involving ostarine.Clin Chim Acta | Case reports | 2024 |
| RAD-140 Drug-Induced Liver Injury.Ochsner J | Case reports | 2022 |
| Liver injury associated with the use of selective androgen receptor modulators and post-cycle therapy: Two case reports and literature review.World J Clin Cases | Case reports | 2021 |
| Drug-Induced Liver Injury From Enobosarm (Ostarine), a Selective Androgen Receptor Modulator.ACG Case Rep J | Case reports | 2021 |
| Selective Androgen Receptor Modulators (SARMs) in Sport: Patterns of Use, Product Contamination, Health Risks and Doping-Control Implications.Drug Test Anal | Review of studies | 2026 |
| An Update on the Role of Androgens and Androgen Receptor in Triple-Negative Breast Cancer.Cells | Review of studies | 2026 |
| Sarcopenia in Aging: Pathogenesis, Diagnosis, and Emerging Therapeutic Frontiers.Mol Imaging Biol | Review of studies | 2026 |
| Pharmacological intervention: Challenges and promising outcomes for fat loss and preservation of lean body mass in the treatment of overweight and type 2 diabetes.Diabetes Obes Metab | Review of studies | 2026 |
| Pharmacologic Treatments for the Preservation of Lean Body Mass During Weight Loss.J Clin Med | Review of studies | 2026 |
| Current Status and Advances in Anti-Androgen Therapy for Triple-Negative Breast Cancer.Curr Med Sci | Review of studies | 2025 |
| The Potential of SARMs and Antimyostatin Agents in Addressing Lean Body Mass Loss From GLP-1 Agonists: A Literature Review.J Diabetes | Review of studies | 2025 |
| Selective androgen receptor modulators (SARMs) - potential anabolic drugs for the treatment of cachexia and frailty syndrome.Endokrynol Pol | Review of studies | 2025 |
| The relationship between muscle mass and function in cancer cachexia: smoke and mirrors?Curr Opin Support Palliat Care | Review of studies | 2018 |
| Pharmacological management of cachexia in adult cancer patients: a systematic review of clinical trials.BMC Cancer | Review of studies | 2018 |
| Detection of SARMs in doping control analysis.Mol Cell Endocrinol | Review of studies | 2018 |
| Overcoming obstacles in the design of cancer anorexia/weight loss trials.Crit Rev Oncol Hematol | Review of studies | 2017 |
| Novel therapeutic options for cachexia and sarcopenia.Expert Opin Biol Ther | Review of studies | 2016 |
| Study Design and Rationale for the Phase 3 Clinical Development Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials).Curr Oncol Rep | Review of studies | 2016 |
| Clinical results in cachexia therapeutics.Curr Opin Clin Nutr Metab Care | Review of studies | 2016 |
| Skeletal muscle atrophy: Potential therapeutic agents and their mechanisms of action.Pharmacol Res | Review of studies | 2015 |
| Treatment of cachexia: An overview of recent developments.Int J Cardiol | Review of studies | 2015 |
| Treatment of cachexia: an overview of recent developments.J Am Med Dir Assoc | Review of studies | 2014 |
| Selective androgen receptor modulators for the prevention and treatment of muscle wasting associated with cancer.Curr Opin Support Palliat Care | Review of studies | 2013 |
| Highlights of mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology.Arch Med Sci | Review of studies | 2013 |
| Highlights of the mechanistic and therapeutic cachexia and sarcopenia research 2010 to 2012 and their relevance for cardiology.Int J Cardiol | Review of studies | 2013 |
| Miscellaneous agents--cytotoxics and hormonal agents.J Thorac Oncol | Review of studies | 2012 |
| An update on promising agents for the treatment of cancer cachexia.Curr Opin Support Palliat Care | Review of studies | 2009 |
| Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia.Future Oncol | Review of studies | 2009 |
| Improvement of Bone Healing by Combined Treatment with Selective Androgen and Estrogen Receptor Modulators in Female and Male Rats.Calcif Tissue Int | In animals | 2026 |
| Comprehensive IM-MS approach for SARMs detection in urine: building CCS databases to support food safety monitoring.Food Addit Contam Part A Chem Anal Control Expo Risk Assess | In animals | 2026 |
| Effect of ostarine on glucose level, lipid profile, and osteoporosis in streptozotocin induced diabetic male rats.Can J Physiol Pharmacol | In animals | 2026 |
| Effects of Combined Treatment With Selective Androgen and Estrogen Receptor Modulators Ostarine and Raloxifen on Bone Tissue In Ovariectomized Rats.Calcif Tissue Int | In animals | 2025 |
| Ostarine blunts the effect of endurance training on submaximal endurance in rats.Naunyn Schmiedebergs Arch Pharmacol | In animals | 2024 |
| Advantage of ostarine over raloxifene and their combined treatments for muscle of estrogen-deficient rats.J Endocrinol Invest | In animals | 2024 |
| Sex-specific cytotoxicity of ostarine in cardiomyocytes.Mol Cell Endocrinol | In animals | 2023 |
| Treatment of osteoporosis using a selective androgen receptor modulator ostarine in an orchiectomized rat model.Endocrine | In animals | 2023 |
| Ostarine does not enhance the metabolic effect of exercise in obese rats.J Physiol Pharmacol | In animals | 2023 |
| A combined treatment with selective androgen and estrogen receptor modulators prevents bone loss in orchiectomized rats.J Endocrinol Invest | In animals | 2022 |
| Combination of selective androgen and estrogen receptor modulators in orchiectomized rats.J Endocrinol Invest | In animals | 2022 |
| Ostarine-Induced Myogenic Differentiation in C2C12, L6, and Rat Muscles.Int J Mol Sci | In animals | 2022 |
| Effect of Selective Androgen Receptor Modulator Enobosarm on Bone Healing in a Rat Model for Aged Male Osteoporosis.Calcif Tissue Int | In animals | 2020 |
| Ostarine and Ligandrol Improve Muscle Tissue in an Ovariectomized Rat Model.Front Endocrinol (Lausanne) | In animals | 2020 |
| Development of a multi-residue high-throughput UHPLC-MS/MS method for routine monitoring of SARM compounds in equine and bovine blood.Drug Test Anal | In animals | 2020 |
| Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor.EMBO Mol Med | In animals | 2020 |
| The Selective Androgen Receptor Modulator Ostarine Improves Bone Healing in Ovariectomized Rats.Calcif Tissue Int | In animals | 2020 |
| Synthesis of Aryl Propionamide Scaffold Containing a Pentafluorosulfanyl Moiety as SARMs.Molecules | In animals | 2019 |
| Effect of ostarine (enobosarm/GTX024), a selective androgen receptor modulator, on adipocyte metabolism in Wistar rats.J Physiol Pharmacol | In animals | 2019 |
| Specific characterization of non-steroidal selective androgen peceptor modulators using supercritical fluid chromatography coupled to ion-mobility mass spectrometry: application to the detection of enobosarm in bovine urine.Drug Test Anal | In animals | 2017 |
| Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry.Rapid Commun Mass Spectrom | In animals | 2016 |
| Enobosarm (GTx-024) Modulates Adult Skeletal Muscle Mass Independently of the Androgen Receptor in the Satellite Cell Lineage.Endocrinology | In animals | 2015 |
| Absorption, distribution, metabolism and excretion of the novel SARM GTx-024 [(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide] in rats.Xenobiotica | In animals | 2013 |
| Limitations of Molecular Docking in Predicting the Selectivity of Selective Androgen Receptor Modulators (SARMs): A Comparative Study of YK11 and Ostarine Across Five Nuclear Receptors.Int J Mol Sci | Other paper | 2026 |
| Manhole Sampling at Gyms and Sports Centers in Denmark: A Pilot Study Using Wastewater Analysis as a Tool for Monitoring the Use of Performance-Enhancing Drugs.Drug Test Anal | Other paper | 2026 |
| Muscle Loss in Obesity Therapy as a Therapeutic Target: Trial Design and Endpoints for Regulatory Discussions.J Cachexia Sarcopenia Muscle | Other paper | 2025 |
| A Computational and In Vitro Appraisal of Ostarine to Target Androgen Receptor in Glioma C6 Cells.Cell Biochem Biophys | Other paper | 2025 |
| SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON.Drug Test Anal | Other paper | 2025 |
| Rapid detection of illegal selective androgen receptor modulators in unregistered supplements using a combination of selected solid-state analytical methods.ADMET DMPK | Other paper | 2025 |
| Sarcopenia in Ageing and Chronic Illness: Trial Endpoints and Regulatory Issues.J Cachexia Sarcopenia Muscle | Other paper | 2025 |
| Detection of anabolic agents including selective androgen receptor modulators in samples outside of sport.Drug Test Anal | Other paper | 2024 |
| The disordering effect of SARMs on a biomembrane model.Phys Chem Chem Phys | Other paper | 2024 |
| In Vitro and In Vivo Human Metabolism of Ostarine, a Selective Androgen Receptor Modulator and Doping Agent.Int J Mol Sci | Other paper | 2024 |
| Evidence of ostarine excretion in oral fluid after a single controlled oral administration.Clin Chim Acta | Other paper | 2024 |
| A screening method for the quantitative determination of selective androgen receptor modulators (SARMs) in capsules by high resolution 19F- and 1H-NMR spectroscopy.Anal Methods | Other paper | 2024 |
| An Ultra-High-Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry Method with Online Solid-Phase Extraction Sample Preparation for the High-Throughput and Sensitive Determination of Ostarine in Human Urine.Methods Protoc | Other paper | 2024 |
| Selective Androgen Receptor Modulators Combined with Treadmill Exercise Have No Bone Benefit in Healthy Adult Rats.Pharmaceuticals (Basel) | Other paper | 2023 |
| Molecular docking analysis of MCL-1 inhibitors for breast cancer management.Bioinformation | Other paper | 2023 |
| The forensic response after an adverse analytical finding (doping) involving a selective androgen receptor modulator (SARM) in human athlete.J Pharm Biomed Anal | Other paper | 2022 |
| Imaging Androgen Receptors in Breast Cancer with 18F-Fluoro-5α-Dihydrotestosterone PET: A Pilot Study.J Nucl Med | Other paper | 2022 |
| Development and validation of SARMs and metabolic modulators screening in hair using UHPLC-MS/MS: Application to a doping case and first identification of S23 in authentic human hair.J Chromatogr B Analyt Technol Biomed Life Sci | Other paper | 2021 |
| Ostarine attenuates pyocyanin in Pseudomonas aeruginosa by interfering with quorum sensing systems.J Antibiot (Tokyo) | Other paper | 2021 |
| Peroxisome Proliferator-Activated Receptor Delta Agonist (PPAR- δ) and Selective Androgen Receptor Modulator (SARM) Abuse: Clinical, Analytical and Biological Data in a Case Involving a Poisonous Combination of GW1516 (Cardarine) and MK2866 (Ostarine).Toxics | Other paper | 2021 |
| Novel Agents Show Promise Against Acquired Endocrine Resistance in ER+ Advanced Breast Cancer.Oncologist | Other paper | 2021 |
| Perspectives in Evaluating Selective Androgen Receptor Modulators in Human Hair: A Short Communication.Ther Drug Monit | Other paper | 2021 |
| Simultaneous detection of different chemical classes of selective androgen receptor modulators in urine by liquid chromatography-mass spectrometry-based techniques.J Pharm Biomed Anal | Other paper | 2021 |
| High-throughput liquid chromatography tandem mass spectrometry assay as initial testing procedure for analysis of total urinary fraction.Drug Test Anal | Other paper | 2021 |
| Elimination profiles of microdosed ostarine mimicking contaminated products ingestion.Drug Test Anal | Other paper | 2020 |
| Identification of S22 (ostarine) in human nails and hair using LC-HRMS. Application to two authentic cases.Drug Test Anal | Other paper | 2020 |
| Enhanced UHPLC-MS/MS screening of selective androgen receptor modulators following urine hydrolysis.MethodsX | Other paper | 2020 |
| Computed tomographic assessment of lean body mass in patients on selective androgen receptor modulator.Clin Imaging | Other paper | 2020 |
| A novel approach to the quantification of urinary aryl-propionamide-derived SARMs by UHPLC-MS/MS.Biomed Chromatogr | Other paper | 2020 |
| A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer.Eur J Med Chem | Other paper | 2019 |
| Selective androgen receptor modulators (SARMs) have specific impacts on the mouse uterus.J Endocrinol | Other paper | 2019 |
| TiO2 Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry.J Am Soc Mass Spectrom | Other paper | 2019 |
| Evaluation of ostarine as a selective androgen receptor modulator in a rat model of postmenopausal osteoporosis.J Bone Miner Metab | Other paper | 2019 |
| Novel Trifluoromethylated Enobosarm Analogues with Potent Antiandrogenic Activity In Vitro and Tissue Selectivity In Vivo.Mol Cancer Ther | Other paper | 2018 |
| Silver linings on the horizon: highlights from the 10th Cachexia Conference.J Cachexia Sarcopenia Muscle | Other paper | 2018 |
| Prevention of body weight loss and sarcopenia by a novel selective androgen receptor modulator in cancer cachexia models.Oncol Lett | Other paper | 2017 |
| Analytical strategies to detect enobosarm administration in bovines.Food Addit Contam Part A Chem Anal Control Expo Risk Assess | Other paper | 2017 |
| Tissue Selective Androgen Receptor Modulators (SARMs) Increase Pelvic Floor Muscle Mass in Ovariectomized Mice.J Cell Biochem | Other paper | 2017 |
| Highlights from the 7th Cachexia Conference: muscle wasting pathophysiological detection and novel treatment strategies.J Cachexia Sarcopenia Muscle | Other paper | 2014 |
| Enobosarm (GTx-024, S-22): a potential treatment for cachexia.Future Oncol | Other paper | 2014 |
| Computer-aided (in silico) approaches in the mode-of-action analysis and safety assessment of ostarine and 4-methylamphetamine.Hum Psychopharmacol | Other paper | 2013 |
| Selective androgen receptor modulators: in vitro and in vivo metabolism and analysis.Food Addit Contam Part A Chem Anal Control Expo Risk Assess | Other paper | 2013 |
| Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet.Drug Test Anal | Other paper | 2011 |