| The effect of levocarnitine supplementation on dialysis-related hypotension: A systematic review, meta-analysis, and trial sequential analysis.PLoS One | Pooled analysis | 2022 |
| Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.J Clin Sleep Med | Pooled analysis | 2021 |
| Effect of L-carnitine on liver enzymes and biochemical factors in hepatic encephalopathy: A systematic review and meta-analysis.J Gastroenterol Hepatol | Pooled analysis | 2019 |
| Efficacy of l-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis | Pooled analysis | 2019 |
| Impact of L-carnitine on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials.Sci Rep | Pooled analysis | 2016 |
| Acetyl-L-carnitine in the treatment of peripheral neuropathic pain: a systematic review and meta-analysis of randomized controlled trials.PLoS One | Pooled analysis | 2015 |
| Influence of L-carnitine supplementation on serum lipid profile in hemodialysis patients: a systematic review and meta-analysis.Kidney Blood Press Res | Pooled analysis | 2013 |
| Interventions for sexual dysfunction following treatments for cancer.Cochrane Database Syst Rev | Pooled analysis | 2007 |
| Effectiveness of L-Carnitine for the Treatment of Erythropoietin-Resistant Renal Anemia: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial.J Ren Nutr | Random groups | 2026 |
| Kidney function as a key driver of the pharmacokinetic response to high-dose L-carnitine in septic shock.Pharmacotherapy | Random groups | 2023 |
| Caffeine ingestion stimulates plasma carnitine clearance in humans.Physiol Rep | Random groups | 2023 |
| Effects of Reducing L-Carnitine Supplementation on Carnitine Kinetics and Cardiac Function in Hemodialysis Patients: A Multicenter, Single-Blind, Placebo-Controlled, Randomized Clinical Trial.Nutrients | Random groups | 2021 |
| L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility.PLoS One | Random groups | 2020 |
| Effect of Levocarnitine on the Therapeutic Efficacy of Conventional Therapy in Children with Dilated Cardiomyopathy: Results of a Randomized Trial in 29 Children.Paediatr Drugs | Random groups | 2018 |
| Modulatory role of L-carnitine against microcystin-LR-induced immunotoxicity and oxidative stress in common carp.Fish Physiol Biochem | Random groups | 2017 |
| Physiological Intra-Cytoplasmic Sperm Injection (PICSI) outcomes after oral pretreatment and semen incubation with myo-inositol in oligoasthenoteratozoospermic men: results from a prospective, randomized controlled trial.Eur Rev Med Pharmacol Sci | Random groups | 2017 |
| L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study.Nutr J | Random groups | 2014 |
| Adding L-carnitine to clomiphene resistant PCOS women improves the quality of ovulation and the pregnancy rate. A randomized clinical trial.Eur J Obstet Gynecol Reprod BiolRetracted | Random groups | 2014 |
| [Influence of levocarnitine on heart function and endocrine among patients with heart failure].Zhonghua Liu Xing Bing Xue Za Zhi | Random groups | 2013 |
| L-carnitine treatment in incident hemodialysis patients: the multicenter, randomized, double-blinded, placebo-controlled CARNIDIAL trial.Clin J Am Soc Nephrol | Random groups | 2012 |
| [Short-term medication of L-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia].Zhonghua Nan Ke Xue | Random groups | 2012 |
| [Use of L-carnitine before percutaneous epididymal sperm aspiration-intracytoplasmic sperm injection for obstructive azoospermia].Zhonghua Nan Ke Xue | Random groups | 2010 |
| Effects of in ovo injection of L-carnitine on subsequent broiler chick tissue nutrient profiles.Poult Sci | Random groups | 2010 |
| Acetyl-L-carnitine in the management of pain during methadone withdrawal syndrome.Clin Neuropharmacol | Random groups | 2009 |
| Insulin action on glucose and protein metabolism during L-carnitine supplementation in maintenance haemodialysis patients.Nephrol Dial Transplant | Random groups | 2008 |
| A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection.HIV Med | Random groups | 2007 |
| Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients.Clin Exp Rheumatol | Random groups | 2007 |
| Imbalance between nitric oxide generation and oxidative stress in patients with peripheral arterial disease: effect of an antioxidant treatment.J Vasc Surg | Random groups | 2006 |
| Results of a single blind, randomized, placebo-controlled clinical trial to study the effect of intravenous L-carnitine supplementation on health-related quality of life in Indian patients on maintenance hemodialysis.Indian J Med Sci | Random groups | 2006 |
| Propionyl-L-carnitine therapy: effects on endothelin-1 and homocysteine levels in patients with peripheral arterial disease and end-stage renal disease.Kidney Blood Press Res | Random groups | 2006 |
| A randomised, controlled clinical trial evaluating changes in therapeutic efficacy and oxidative parameters after treatment with propionyl L-carnitine in patients with peripheral arterial disease requiring haemodialysis.Drugs Aging | Random groups | 2006 |
| Effects of carnitine supplementation on muscle metabolism by the use of magnetic resonance spectroscopy and near-infrared spectroscopy in end-stage renal disease.Nephron Clin Pract | Random groups | 2004 |
| Nutritional effects of carnitine supplementation in hemodialysis patients.Clin Nephrol | Random groups | 2003 |
| Intravenous L-carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in hemodialysis patients.Am J Kidney Dis | Random groups | 2001 |
| Evaluation of the effect of intravenous l-carnitine on quality of life in chronic hemodialysis patients.Clin Nephrol | Random groups | 2000 |
| Pharmacokinetics of propionyl-L-carnitine in humans: evidence for saturable tubular reabsorption.Br J Clin Pharmacol | Random groups | 2000 |
| Effect of carnitine on muscular glutamate uptake and intramuscular glutathione in malignant diseases.Br J Cancer | Random groups | 2000 |
| Does left ventricular function improve with L-carnitine after acute myocardial infarction?J Postgrad Med | Random groups | 1999 |
| Anemia and carnitine supplementation in hemodialyzed patients.Kidney Int Suppl | Random groups | 1999 |
| Anti-ischaemic efficacy of L-propionylcarnitine--a promising novel metabolic approach to ischaemia?Eur Heart J | Random groups | 1996 |
| Effect of intravenous L-carnitine on carnitine homeostasis and fuel metabolism during exercise in humans.Clin Pharmacol Ther | Random groups | 1994 |
| The effect of L-carnitine, administered through intravenous infusion of glucose, on both glucose and insulin levels in healthy subjects.Drugs Exp Clin Res | Random groups | 1994 |
| [Anti-arrhythmia treatment using L-carnitine in acute myocardial infarct].Schweiz Med Wochenschr | Random groups | 1992 |
| Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects.Kidney Int | Random groups | 1990 |
| Multicenter trial of L-carnitine in maintenance hemodialysis patients. I. Carnitine concentrations and lipid effects.Kidney Int | Random groups | 1990 |
| Effect of intravenous L-carnitine on growth parameters and fat metabolism during parenteral nutrition in neonates.JPEN J Parenter Enteral Nutr | Random groups | 1990 |
| Effect of L-carnitine on the reactive hyperemia in patients affected by peripheral vascular disease: a double-blind, crossover study.Angiology | Random groups | 1989 |
| High doses of L-carnitine in acute myocardial infarction: metabolic and antiarrhythmic effects.Eur Heart J | Random groups | 1989 |
| L-carnitine addition to dialysis fluid. A therapeutic alternative for hemodialysis patients.Nephron | Random groups | 1989 |
| Effect of L-carnitine on ethanol and acetate plasma levels after oral administration of ethanol in humans.Alcohol Clin Exp Res | Random groups | 1988 |
| Carnitine deficiency in premature infants receiving total parenteral nutrition: effect of L-carnitine supplementation.J Pediatr | Random groups | 1983 |
| Effects of L-Carnitine Supplementation in Patients Receiving Hemodialysis or Peritoneal Dialysis.Nutrients | No random groups | 2020 |
| [A study of the efficacy and safety of L-carnitine in patients with ischemic stroke in the early rehabilitation period].Zh Nevrol Psikhiatr Im S S Korsakova | No random groups | 2017 |
| Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network.Cancer Chemother Pharmacol | No random groups | 2014 |
| Carnitine supplementation improves cardiac strain rate in children on chronic hemodialysis.Pediatr Nephrol | No random groups | 2012 |
| L-carnitine supplementation and EPO requirement in children on chronic hemodialysis.Pediatr Nephrol | No random groups | 2010 |
| [Clinical efficacy of intravenous L-carnitine in patients with right-sided heart failure induced by pulmonary arterial hypertension].Zhonghua Xin Xue Guan Bing Za Zhi | No random groups | 2010 |
| L-Carnitine supplementation during suckling intensifies the early postnatal skeletal myofiber formation in piglets of low birth weight.J Anim Sci | No random groups | 2009 |
| [Study of aerobic capacity in chronic hemodialized patients: effect of L-carnitine supplementation].Med Clin (Barc) | No random groups | 2008 |
| Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment.Cancer Chemother Pharmacol | No random groups | 2007 |
| Effects of a single, short intravenous dose of acetyl-L-carnitine on pattern-reversal visual-evoked potentials in cirrhotic patients with hepatic encephalopathy.Clin Exp Pharmacol Physiol | No random groups | 2006 |
| Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy.Urology | No random groups | 2005 |
| L-carnitine infusions may suppress serum C-reactive protein and improve nutritional status in maintenance hemodialysis patients.J Ren Nutr | No random groups | 2005 |
| The effect of L-carnitine on insulin resistance in hemodialysed patients with chronic renal failure.J Nephrol | No random groups | 1999 |
| Superiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over study.Eur Heart J | No random groups | 1992 |
| Evaluation of the effect of intravenous L-carnitine therapy on function, structure and fatty acid metabolism of skeletal muscle in patients receiving chronic hemodialysis.Nephron | No random groups | 1991 |
| Spatial-frequency-dependent changes in the human pattern electroretinogram after acute acetyl-L-carnitine administration.Graefes Arch Clin Exp Ophthalmol | No random groups | 1991 |
| Studies concerning some acute biological changes after endovenous administration of 1 g l-carnitine, in elite athletes.Physiologie | No random groups | 1987 |
| Fat metabolism following an intravenous bolus dose of a fat emulsion and carnitine.Clin Physiol | No random groups | 1984 |
| Association between Levocarnitine Treatment and the Change in Knee Extensor Strength in Patients Undergoing Hemodialysis: A Post-Hoc Analysis of the Osaka Dialysis Complication Study (ODCS).Nutrients | Group followed over time | 2022 |
| Glutaric acidemia type 2 presenting as a surgical acute abdomen: a case of unnecessary exploratory laparotomy in an adult.Arch Clin Cases | Case reports | 2026 |
| Multimodal Abdominal Contouring Combining Injectable Lipolysis, Ultrasonic Cavitation, and Neuromuscular Electrical Stimulation: A Retrospective Case Series.Clin Cosmet Investig Dermatol | Case reports | 2026 |
| Coexistence of VLCAD deficiency and Hashimoto's thyroiditis: a rare case report.BMC Endocr Disord | Case reports | 2026 |
| Massive Valproic Acid Overdose With Confirmed Pharmacobezoar Formation and Neuromuscular Toxicity: A Case Report and Literature Review.Cureus | Case reports | 2025 |
| Low excretor glutaric acidemia type 1 with transient lesions in the basal ganglia.Brain Dev | Case reports | 2025 |
| When Overdose Strikes: Successful Use of Hemodialysis in Valproic Acid Toxicity.Cureus | Case reports | 2025 |
| L-Carnitine and Acetyl-L-Carnitine: A Novel Approach to Treating Male Infertility with Abnormal Sperm Morphology.J Pharm Bioallied Sci | Case reports | 2025 |
| Insulin therapy in acute decompensation of holocarboxylase synthetase deficiency with hyperglycemia and ketoacidosis.Mol Genet Metab Rep | Case reports | 2024 |
| Effective treatment of choreaballism due to an MT-CYB variant with haloperidol, tetrabenazine, and antioxidants.Clin Case Rep | Case reports | 2023 |
| Case report: Tackling the complexities of an extremely premature newborn with intrauterine growth restriction and congenital metabolic disorders through a multidisciplinary approach.Front Pediatr | Case reports | 2023 |
| A case of Fukuyama-type congenital muscular dystrophy with acute carnitine deficiency triggered by fever, vomiting, and gastrointestinal bleeding.Nutrition | Case reports | 2023 |
| Transport and Golgi organization 2 deficiency with a prominent elevation of C14:1 during a metabolic crisis: A case report.JIMD Rep | Case reports | 2023 |
| IARS2-related disease manifesting as sideroblastic anemia and hypoparathyroidism: A case report.Front Pediatr | Case reports | 2022 |
| Rare cause of coronary artery ectasia in children: A case report of methylmalonic acidemia with hyperhomocysteinemia.Front Pediatr | Case reports | 2022 |
| Acute Lymphoblastic Leukemia in Combined Methylmalonic Acidemia and Homocysteinemia (cblC Type): A Case Report and Literature Review.Front Genet | Case reports | 2022 |
| L-Asparaginase-Induced Hepatotoxicity Treated Successfully With L-Carnitine and Vitamin B Infusion.Cureus | Case reports | 2021 |
| L-carnitine supplementation as a potential therapy for suspected hyperammonaemic encephalopathy.J R Coll Physicians Edinb | Case reports | 2019 |
| Isolated subacute combined degeneration in late-onset cobalamin C deficiency in children: Two case reports and literature review.Medicine (Baltimore) | Case reports | 2019 |
| L-carnitine and Vitamin B Complex for PEG-L-asparaginase-Induced Hepatotoxicity.ACG Case Rep J | Case reports | 2019 |
| L-carnitine Improved the Cardiac Function via the Effect on Myocardial Fatty Acid Metabolism in a Hemodialysis Patient.Intern Med | Case reports | 2018 |
| Effects of l-Carnitine Supplementation, Botulinum Neurotoxin Injection, and Rehabilitation for a Chronic Stroke Patient.J Stroke Cerebrovasc Dis | Case reports | 2018 |
| Hemodiafiltration Treatment for Severe Valproic Acid Intoxication: Case Report and Updated Systematic Literature Review.Front Med (Lausanne) | Case reports | 2018 |
| Atypical hemolytic uremic syndrome induced by CblC subtype of methylmalonic academia: A case report and literature review.Medicine (Baltimore) | Case reports | 2017 |
| [Paroxysmal muscle weakness, liver enlargement, and hypoglycemia in a boy].Zhongguo Dang Dai Er Ke Za Zhi | Case reports | 2017 |
| Sudden valproate-induced hyperammonemia managed with L-carnitine in a medically healthy bipolar patient: Essential review of the literature and case report.Medicine (Baltimore) | Case reports | 2017 |
| [Acute brainstem encephalitis and myelitis in a girl with isolated methylmalonic aciduria due to MUT gene defect].Zhongguo Dang Dai Er Ke Za Zhi | Case reports | 2015 |
| First Chinese case of successful pregnancy with combined methylmalonic aciduria and homocystinuria, cblC type.Brain Dev | Case reports | 2015 |
| [A Chinese boy with methylmalonic aciduria cblB type and a novel mutation in the MMAB gene].Zhongguo Dang Dai Er Ke Za Zhi | Case reports | 2015 |
| [Acute encephalopathy induced by vaccination in an infant with methylmalonic aciduria cblA].Zhonghua Er Ke Za Zhi | Case reports | 2015 |
| Children at risk of diabetes type 1. Treatment with acetyl-L-carnitine plus nicotinamide - case reports.J Pediatr Endocrinol Metab | Case reports | 2013 |
| [Leucodystrophy induced by late onset 3-hydroxy-3-methylglutaric aciduria].Zhongguo Dang Dai Er Ke Za Zhi | Case reports | 2011 |
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| Outpatient treatment of propionic acidemia-associated hyperammonemia with N-carbamoyl-L-glutamate in an infant.Clin Ther | Case reports | 2010 |
| Glutaric aciduria type II and narcolepsy in pregnancy.Obstet Gynecol | Case reports | 2008 |
| Two cases of valproic acid poisoning treated with L-carnitine.Hum Exp Toxicol | Case reports | 2007 |
| [Valproate-associated hyperammonemic encephalopathy. Report of one case].Rev Med Chil | Case reports | 2007 |
| Marfanoid features in a child with combined methylmalonic aciduria and homocystinuria (CblC type).J Inherit Metab Dis | Case reports | 2007 |
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| [Fatal lactic acidosis in a patient infected by HIV and treated with stavudine and didanosine].Pathol Biol (Paris) | Case reports | 2000 |
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| Valproic acid overdose and L-carnitine therapy.J Anal Toxicol | Case reports | 1996 |
| Intravenous L-carnitine and acetyl-L-carnitine in medium-chain acyl-coenzyme A dehydrogenase deficiency and isovaleric acidemia.Pediatr Res | Case reports | 1994 |
| Acute effects of acetyl-L-carnitine on regional cerebral blood flow in patients with brain ischaemia.Int J Clin Pharmacol Res | Case reports | 1990 |
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| The effect of intravenous L-carnitine on propionic acid excretion in acute propionic acidaemia.Eur J Pediatr | Case reports | 1984 |
| Carnitine deficiency with hyperbilirubinemia, generalized skeletal muscle weakness and reactive hypoglycemia in a patient on long-term total parenteral nutrition: treatment with intravenous L-carnitine.JPEN J Parenter Enteral Nutr | Case reports | 1983 |
| Metabolomics in chickens: Bridging the gap between genotypes and phenotypes.Poult Sci | Review of studies | 2026 |
| Nutritional Interventions for Patients with Intermittent Claudication: Mechanisms, Clinical Implications, and the Case for Exercise-Adjunct Strategies: A Narrative Review.J Cardiovasc Dev Dis | Review of studies | 2026 |
| The effectiveness and safety of integrative medicine for chronic heart failure: An umbrella review.Complement Ther Med | Review of studies | 2025 |
| L-carnitine for valproic acid-induced toxicity.Br J Clin Pharmacol | Review of studies | 2025 |
| Effects of L-carnitine supplementation on lipid profile in adult patients under hemodialysis: a systematic review and meta-analysis of RCTs.Front Med (Lausanne) | Review of studies | 2024 |
| The management of erectile dysfunction in men with diabetes mellitus unresponsive to phosphodiesterase type 5 inhibitors.Andrology | Review of studies | 2023 |
| Treatment of HMG-CoA Lyase Deficiency-Longitudinal Data on Clinical and Nutritional Management of 10 Australian Cases.Nutrients | Review of studies | 2023 |
| Novel Drugs for the Management of Hepatic Encephalopathy: Still a Long Journey to Travel.J Clin Exp Hepatol | Review of studies | 2022 |
| In ovo Feeding as a Tool for Improving Performance and Gut Health of Poultry: A Review.Front Vet Sci | Review of studies | 2021 |
| Natural products - alpha-lipoic acid and acetyl-L-carnitine - in the treatment of chemotherapy-induced peripheral neuropathy.Eur Rev Med Pharmacol Sci | Review of studies | 2018 |
| l-Carnitine and heart disease.Life Sci | Review of studies | 2018 |
| Systematic review: the treatment of muscle cramps in patients with cirrhosis.Aliment Pharmacol Ther | Review of studies | 2014 |
| Analytical approaches to determination of carnitine in biological materials, foods and dietary supplements.Food Chem | Review of studies | 2014 |
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| Carnitine for fatigue in multiple sclerosis.Cochrane Database Syst Rev | Review of studies | 2012 |
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| Carnitine for fatigue in multiple sclerosis.Cochrane Database Syst Rev | Review of studies | 2010 |
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| L-carnitine supplementation in the dialysis population: are Australian patients missing out?Nephrology (Carlton) | Review of studies | 2008 |
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| Debate forum: levocarnitine therapy is rational and justified in selected dialysis patients.Blood Purif | Review of studies | 2006 |
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| Effect of increased fat availability on metabolism and exercise capacity.Med Sci Sports Exerc | Review of studies | 2002 |
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| Optimizing erythropoietin therapy.Curr Opin Hematol | Review of studies | 1999 |
| Is there a role for adjuvant therapy in patients being treated with epoetin?Nephrol Dial Transplant | Review of studies | 1999 |
| Utilization of lipids during exercise in human subjects: metabolic and dietary constraints.Br J Nutr | Review of studies | 1998 |
| Clinical pharmacokinetics of drugs for Alzheimer's disease.Clin Pharmacokinet | Review of studies | 1995 |
| Protection of the brain by carnitine.Sangyo Eiseigaku Zasshi | Review of studies | 1995 |
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| Bioactive compounds and fatty acid composition in raw and cooked beef with two different ageing periods.Meat Sci | In animals | 2026 |
| Acetyl-L-carnitine protective role in gemcitabine-induced neurotoxicity in an experimental rat model.Open Vet J | In animals | 2026 |
| Morinda officinalis oligosaccharides improves sperm motility via the gut microbiota and the IGF-1/PI3K/mTOR signaling pathway.Front Endocrinol (Lausanne) | In animals | 2025 |
| Mitochondria-targeting compounds for management of metabolic and hemostatic abnormalities associated with heart dysfunctions in experimental type 2 diabetes.Endocr Regul | In animals | 2025 |
| Rumen microbiota-host interactions regulate intramuscular fat deposition in cattle via the alpha-linolenic acid-fatty acid β-oxidation/L-carnitine-MPO axis.Microbiome | In animals | 2025 |
| Integrated Transcriptomic and Metabolomic Analysis of the Mechanism of Intramuscular Fat Differences in Wandong Cattle.Int J Mol Sci | In animals | 2025 |
| Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bovine blood cells during systemic immune challenge.Front Immunol | In animals | 2025 |
| Metabolome and RNA-seq reveal discrepant metabolism and secretory metabolism profile in skeletal muscle between obese and lean pigs at different ages.Sci China Life Sci | In animals | 2025 |
| Intra-amniotic injection of L-carnitine reveals age-related effects on tissue total antioxidant status and increases plasma testosterone levels in male broiler chicks.BMC Vet Res | In animals | 2025 |
| Evaluation of L-carnitine's protective properties against AlCl3-induced brain, liver, and renal toxicity in rats.PLoS One | In animals | 2025 |
| L-carnitine attenuates autophagic flux, apoptosis, and necroptosis in rats with dexamethasone-induced non-alcoholic steatohepatitis.BMC Pharmacol Toxicol | In animals | 2024 |
| Protective effects of L-carnitine against beta-amyloid-induced memory impairment and anxiety-like behavior in a rat model of Alzheimer's disease.Eur J Pharmacol | In animals | 2024 |
| Mechanic evaluation of Wu-Mei-Pill on colitis-associated colorectal cancer: An integrated transcriptomics, metabolomics, and experimental validation study.Phytomedicine | In animals | 2024 |
| Dietary L-carnitine supplementation modifies blood parameters of mid-lactating dairy cows during standardized lipopolysaccharide-induced inflammation.Front Immunol | In animals | 2024 |
| Ameliorative effects of L-carnitine as an antioxidant against testicular toxicity induced by AlCl3 in male albino rats.Eur Rev Med Pharmacol Sci | In animals | 2024 |
| A quality by design approach for the synthesis of palmitoyl-L-carnitine-loaded nanoemulsions as drug delivery systems.Drug Deliv | In animals | 2023 |
| Incorporation of L-Carnitine in the OvSynch protocol enhances the morphometrical and hemodynamic parameters of the ovarian structures and uterus in ewes under summer climatic conditions.BMC Vet Res | In animals | 2023 |
| Acidosis attenuates CPT-I-supported bioenergetics as a potential mechanism limiting lipid oxidation.J Biol Chem | In animals | 2023 |
| Effects of L-carnitine Administration on Sperm and Sex Hormone Levels in a Male Wistar Rat Reproductive System Injury Model in a High-Altitude Hypobaric Hypoxic Environment.Reprod Sci | In animals | 2023 |
| Protective effects of L-carnitine against valproic acid-induced memory impairment and anxiety-like behavior in adult rat.Physiol Behav | In animals | 2022 |
| Rifaximin enhances the L‑carnitine‑mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut‑liver‑muscle axis.Int J Mol Med | In animals | 2022 |
| l-Carnitine ameliorates the osteoporotic changes and protects against simvastatin induced myotoxicity and hepatotoxicity in glucocorticoid-induced osteoporosis in rats.Biomed Pharmacother | In animals | 2022 |
| Anti-kindling effect of Ginkgo biloba leaf extract and L-carnitine in the pentylenetetrazol model of epilepsy.Environ Sci Pollut Res Int | In animals | 2022 |
| Influences of vitamin A, L-carnitine, and folic acid in ovo feeding on embryo and hatchling characteristics and general health status in ducks.Anim Biotechnol | In animals | 2022 |
| Runjing Decoction alleviated cyclophosphamide-induced oligoasthenospermia rats by inhibiting cell apoptosis via RXFP1/AKT/FOXO1 pathway.Andrologia | In animals | 2021 |
| Novel Cardioprotective Effect of L-Carnitine on Obese Diabetic Mice: Regulation of Chemerin and CMKLRI Expression in Heart and Adipose Tissues.Arq Bras Cardiol | In animals | 2021 |
| Effects of dietary l-carnitine supplementation on the response to an inflammatory challenge in mid-lactating dairy cows: Hepatic mRNA abundance of genes involved in fatty acid metabolism.J Dairy Sci | In animals | 2021 |
| Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFκB, autophagy, inflammation and oxidative stress.Metab Brain Dis | In animals | 2021 |
| Time-based investigation of urinary metabolic markers for Type 2 diabetes: Metabolomics approach for diabetes management.Biofactors | In animals | 2021 |
| The Protective Effects of L-Carnitine and Zinc Oxide Nanoparticles Against Diabetic Injury on Sex Steroid Hormones Levels, Oxidative Stress, and Ovarian Histopathological Changes in Rat.Reprod Sci | In animals | 2021 |
| Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain.Int J Mol Sci | In animals | 2021 |
| L-carnitine improves metabolic disorders and regulates apelin and apelin receptor genes expression in adipose tissue in diabetic rats.Physiol Rep | In animals | 2020 |
| The protective role of l-carnitine on spermatogenesis after cisplatin treatment during prepubertal period in rats: A pathophysiological study.Life Sci | In animals | 2020 |
| Effects of dietary choline, betaine, and L-carnitine on the generation of trimethylamine-N-oxide in healthy mice.J Food Sci | In animals | 2020 |
| L-Carnitine and vitamin E ameliorate cardiotoxicity induced by tilmicosin in rats.Environ Sci Pollut Res Int | In animals | 2020 |
| Radioprotective Effects of Amifostine, L-Carnitine and Vitamin E in Preventing Early Salivary Gland Injury due to Radioactive Iodine Treatment.Curr Med Imaging Rev | In animals | 2019 |
| L-carnitine ameliorates peripheral neuropathy in diabetic mice with a corresponding increase in insulin‑like growth factor‑1 level.Mol Med Rep | In animals | 2019 |
| l-Carnitine-induced amelioration of HFD-induced hepatic dysfunction is accompanied by a reduction in hepatic TNF-α and TGF-β1.Biochem Cell Biol | In animals | 2018 |
| The roles of bone morphogenetic protein 2 in perfluorooctanoic acid induced developmental cardiotoxicity and l-carnitine mediated protection.Toxicol Appl Pharmacol | In animals | 2018 |
| Fatty Acid β-Oxidation Is Essential in Leptin-Mediated Oocytes Maturation of Yellow Catfish Pelteobagrus fulvidraco.Int J Mol Sci | In animals | 2018 |
| Effects of dietary lecithin and l-carnitine on fatty acid composition and lipid-metabolic genes expression in subcutaneous fat and longissimus thoracis of growing-finishing pigs.Meat Sci | In animals | 2018 |
| L-carnitine counteracts prepubertal exposure to cisplatin induced impaired sperm in adult rats by preventing germ cell apoptosis.Biotech Histochem | In animals | 2018 |
| The Roles of Reactive Oxygen Species and Nitric Oxide in Perfluorooctanoic Acid-Induced Developmental Cardiotoxicity and l-Carnitine Mediated Protection.Int J Mol Sci | In animals | 2017 |
| Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats.Pain | In animals | 2017 |
| Possible promoting effects of melatonin, leptin and alcar on regeneration of the sciatic nerve.J Chem Neuroanat | In animals | 2017 |
| The Effects of l-Carnitine Against Cyclophosphamide-Induced Injuries in Mouse Testis.Basic Clin Pharmacol Toxicol | In animals | 2017 |
| The Effect of Intravenous L-Carnitine on the Vasospasm Process in the Experimental Subarachnoid Hemorrhage Model.Turk Neurosurg | In animals | 2017 |
| Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage.Chem Biol Interact | In animals | 2016 |
| Changes in the levels of l-carnitine, acetyl-l-carnitine and propionyl-l-carnitine are involved in perfluorooctanoic acid induced developmental cardiotoxicity in chicken embryo.Environ Toxicol Pharmacol | In animals | 2016 |
| Examining the protective effects of acetyl l-carnitine on cisplatin-induced uterine tube toxicity.J Obstet Gynaecol | In animals | 2016 |
| Effects of Carnitine on Valproic Acid Pharmacokinetics in Rats.J Pharm Sci | In animals | 2016 |
| The cardioprotective effects of L-carnitine on rat cardiac injury, apoptosis, and oxidative stress caused by amethopterin.Environ Sci Pollut Res IntRetracted | In animals | 2016 |
| [Metabolomics analysis on serum biomarkers timing characteristics of type 2 diabetic rats intervened by exercise].Zhongguo Ying Yong Sheng Li Xue Za Zhi | In animals | 2016 |
| Molecular and biochemical evidence on the protection of cardiomyocytes from phosphine-induced oxidative stress, mitochondrial dysfunction and apoptosis by acetyl-L-carnitine.Environ Toxicol Pharmacol | In animals | 2016 |
| Nephroprotective potential of carnitine against glycerol and contrast-induced kidney injury in rats through modulation of oxidative stress, proinflammatory cytokines, and apoptosis.Br J Radiol | In animals | 2016 |
| Prophylactic and Therapeutic Potential of Acetyl-L-carnitine against Acetaminophen-Induced Hepatotoxicity in Mice.J Biochem Mol Toxicol | In animals | 2016 |
| The chemoprotective effects of L-carnitine against genotoxicity induced by diazinon in rat blood lymphocyte.Toxicol Ind HealthRetracted | In animals | 2015 |
| Histopathological and electrophysiological indices of rotenone-evoked dopaminergic toxicity: Neuroprotective effects of acetyl-L-carnitine.Neurosci Lett | In animals | 2015 |
| Skeletal muscle phenotype affects fasting-induced mitochondrial oxidative phosphorylation flexibility in cold-acclimated ducklings.J Exp Biol | In animals | 2015 |
| Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice.Toxicol Appl Pharmacol | In a lab dish | 2019 |
| Acetyl-L-carnitine and oxaloacetate in post-treatment against LTP impairment in a rat ischemia model. An in vitro electrophysiological study.J Neural Transm (Vienna) | In a lab dish | 2015 |
| Enteric neuropathy can be induced by high fat diet in vivo and palmitic acid exposure in vitro.PLoS One | In a lab dish | 2013 |
| Enhanced bioavailability of L-carnitine after painless intradermal delivery vs. oral administration in rats.Pharm Res | In a lab dish | 2011 |
| Behavior of acetyl-L-carnitine injections (Nicetile fiale) with different drugs used for combined therapy.Adv Ther | In a lab dish | 2010 |
| Carnitine deprivation adversely affects cardiac performance in the lipopolysaccharide- and hypoxia/reoxygenation-stressed piglet heart.Shock | In a lab dish | 1999 |
| Carnitine supplementation improves myocardial function in hearts from ischemic diabetic and euglycemic rats.Ann Thorac Surg | In a lab dish | 1998 |
| Influence of L-carnitine on CD95 cross-lining-induced apoptosis and ceramide generation in human cell lines: correlation with its effects on purified acidic and neutral sphingomyelinases in vitro.Proc Assoc Am Physicians | In a lab dish | 1997 |
| Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.J Mol Cell Cardiol | In a lab dish | 1992 |
| Characterization of overt carnitine palmitoyltransferase in rat platelets; involvement of insulin on its regulation.Mol Cell Biochem | In a lab dish | 1991 |
| Effects of in vivo and in vitro treatment with L-carnitine on isolated hearts from chronically diabetic rats.Can J Physiol Pharmacol | In a lab dish | 1990 |
| [Effects of levocarnitine chloride (LC-80) on the cardiovascular system].Nihon Yakurigaku Zasshi | In a lab dish | 1989 |
| L-carnitine treatment improves cardiac performance and restores high-energy phosphate pools in cardiomyopathic Syrian hamster.Circ Res | In a lab dish | 1987 |
| The effect of glucagon treatment and starvation of virgin and lactating rats on the rates of oxidation of octanoyl-L-carnitine and octanoate by isolated liver mitochondria.Biochem J | In a lab dish | 1980 |
| [Clinical and genetic characteristics of children with methylmalonic acidemia presenting as spastic paraplegia].Zhonghua Yi Xue Za Zhi | Other paper | 2026 |
| Acute Hepatocellular Drug-induced Liver Injury following Cosmetic Liquid Lipo Injection Complicated by Anaphylactic Reaction to N-acetylcysteine.Ann Afr Med | Other paper | 2026 |
| Differential activation of TCA cycle activity and PDH flux by dichloroacetate in skeletal muscle measured by hyperpolarized [2-13C,3-2H3]pyruvate.iScience | Other paper | 2026 |
| Effects of L-Carnitine and Fenofibrate on Lipid Metabolism, Oxidative Status, and Flesh Quality of Yellow River Carp (Cyprinus carpio).Aquac Nutr | Other paper | 2026 |
| Changes in hepatic L-carnitine levels in people with metabolic dysfunction-associated steatotic liver disease (MASLD) assessed by magnetic resonance techniques.Sci Rep | Other paper | 2026 |
| L-carnitine ameliorates fibrosis and reproductive dysfunction in intrauterine adhesion via restoration of mitochondrial fatty acid oxidation.Biol Reprod | Other paper | 2026 |
| Clinical Efficacy of Levocarnitine-Alprostadil Combination Therapy on Indicators of Renal Function, Oxidant-Antioxidant Balance, and Systemic Inflammation in Patients with End-Stage Diabetic Nephropathy.Ther Clin Risk Manag | Other paper | 2026 |
| Multi-Omics Integration Reveals Key Genes, Metabolites and Pathways Underlying Meat Quality and Intramuscular Fat Deposition Differences Between Tibetan Pigs and Duroc × Tibetan Crossbred Pigs.Animals (Basel) | Other paper | 2026 |
| Establishment of a LC-MS/MS method for the simultaneous quantitative determination of trimethylamine N-oxide and four precursors in human saliva.J Chromatogr B Analyt Technol Biomed Life Sci | Other paper | 2026 |
| Randomized Clinical Trial for the Optimization of Dyslipidemia Management in Patients with End-Stage Renal Disease Undergoing In-Hospital Maintenance Hemodialysis Therapy.Pharmaceutics | Other paper | 2025 |
| Metabolomic Profiling for Predicting Coronary Artery Aneurysms and IVIG Resistance in Kawasaki Disease- An Exploratory Study.J Cardiovasc Transl Res | Other paper | 2025 |
| What are the best clinical management strategies for cardiomyopathy? an umbrella review of systematic reviews and meta-analyses.Front Pharmacol | Other paper | 2025 |
| CPT1A mediated preservation of mitochondrial inhibits pyroptosis in pancreatic acinar cells.Front Cell Dev Biol | Other paper | 2025 |
| Long-term outcome of CblC deficiency complicated with pulmonary hypertension.Orphanet J Rare Dis | Other paper | 2025 |
| Efficacy of Intravenous Versus Oral Administration of Levocarnitine in Maintenance Hemodialysis Patients: A Randomized Controlled Trial Investigating Therapeutic Approaches to Renal Anemia.Health Sci Rep | Other paper | 2025 |
| Multi-functional Chitosan Polymeric Micelles for improving the oral bioavailability of Paclitaxel based on synergistic effect.Drug Deliv Transl Res | Other paper | 2025 |
| Optimizing Assisted Reproductive Techniques: The Role of L-Carnitine, Acetyl-L-Carnitine, and IMSI in Managing High-Sperm DNA Fragmentation.J Pharm Bioallied Sci | Other paper | 2024 |
| The effect of L-carnitine in reactive oxygen species reduction and apoptotic gene expression in mice after cyclophosphamide: An experimental study.Int J Reprod Biomed | Other paper | 2024 |
| The Pharmacokinetics and Liver-Targeting Evaluation of Silybin Liposomes Mediated by the NTCP/OCTN2 Dual Receptors.Mol Pharm | Other paper | 2024 |
| Targeting Parkin-regulated metabolomic change in cartilage in the treatment of osteoarthritis.iScience | Other paper | 2024 |
| Effects of combination of melatonin and L-carnitine on in vitro maturation in mouse oocytes: An experimental study.Int J Reprod Biomed | Other paper | 2024 |
| The MMACHC variant c.158T>C: Mild clinical and biochemical phenotypes and marked hydroxocobalamin response in cblC patients.Mol Genet Metab | Other paper | 2024 |
| L-carnitine fails to rescue chemotherapy injured ovaries by epigenetic changes of transcription factors.Gene | Other paper | 2024 |
| The intestinal microbial metabolite acetyl l-carnitine improves gut inflammation and immune homeostasis via CADM2.Biochim Biophys Acta Mol Basis Dis | Other paper | 2024 |
| Clinical and electroencephalogram characteristics of methylmalonic acidemia with MMACHC and MUT gene mutations.BMC Pediatr | Other paper | 2024 |
| Database screening as a strategy to identify endogenous candidate metabolites to probe and assess mitochondrial drug toxicity.Sci Rep | Other paper | 2023 |
| Effect of Micronutrients and L-Carnitine as Antioxidant on Sperm Parameters, Genome Integrity, and ICSI Outcomes: Randomized, Double-Blind, and Placebo-Controlled Clinical Trial.Antioxidants (Basel) | Other paper | 2023 |
| Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System.Int J Mol Sci | Other paper | 2023 |
| Real-world practice in Peyronie's disease management: Results from a national survey of urologists.Andrology | Other paper | 2023 |
| Dietary administration of l-carnitine during the fattening period of early feed restricted lambs modifies lipid metabolism and meat quality.Meat Sci | Other paper | 2023 |
| Detection and alterations of acetylcarnitine (AC) in human liver by 1 H MRS at 3T after supplementation with l-carnitine.Magn Reson Med | Other paper | 2023 |
| The effect of sodium benzoate, L-carnitine, and phenylacetate on valproate-induced hyperammonemia in Male Wistar rats.Int J Physiol Pathophysiol Pharmacol | Other paper | 2022 |
| Levocarnitine supplementation for management of hypertriglyceridemia in patients receiving parenteral nutrition.Nutr Clin Pract | Other paper | 2022 |
| [Effects and molecular mechanism of exogenous L-carnitine on excessive endoplasmic reticulum stress-mediated hepatic pyroptosis in severely scald rats].Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi | Other paper | 2022 |
| Effects of High Flux Hemodialysis Combined with L-Carnitine on Microinflammation and Arteriovenous Fistula in Maintenance Hemodialysis Patients.Evid Based Complement Alternat MedRetracted | Other paper | 2022 |
| [Xianfang Huoming Decoction improves sperm quality in asthenospermia mice: An investigation based on the detoxification and sperm-nourishing method].Zhonghua Nan Ke Xue | Other paper | 2022 |
| Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.Andrology | Other paper | 2022 |
| Effects of Lactate Administration on Mitochondrial Respiratory Function in Mouse Skeletal Muscle.Front Physiol | Other paper | 2022 |
| Hepatocyte-Derived L-Carnitine Restricts Hepatitis B Surface Antigen Loss Through an Immunosuppressive Effect on Germinal Center-Related Immune Cells.J Infect Dis | Other paper | 2022 |
| Comparisons of carcass traits, meat quality, and serum metabolome between Shaziling and Yorkshire pigs.Anim Nutr | Other paper | 2022 |
| Dietary Administration of L-Carnitine During the Fattening Period of Early Feed Restricted Lambs Modifies Ruminal Fermentation but Does Not Improve Feed Efficiency.Front Physiol | Other paper | 2022 |
| [Antiastenic effect of sequential levocarnitine and acetylcarnitine therapy in patients with cardiovascular diseases].Zh Nevrol Psikhiatr Im S S Korsakova | Other paper | 2022 |
| Quantitation of Butyrylcarnitine, Isobutyrylcarnitine, and Glutarylcarnitine in Urine Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS).Methods Mol Biol | Other paper | 2022 |
| Therapeutic effects of silver nanoparticle and L-carnitine on aerobic vaginitis in mice: an experimental study.Bioimpacts | Other paper | 2022 |
| Biological Distribution of Orally Administered [123I]MIBG for Estimating Gastrointestinal Tract Absorption.Pharmaceutics | Other paper | 2021 |
| Red-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice.Front Nutr | Other paper | 2021 |
| [Clinical and genetic studies on 76 patients with hydrocephalus caused by methylmalonic acidemia combined with homocysteinuria].Zhonghua Er Ke Za Zhi | Other paper | 2021 |
| Effect of levocarnitine supplementation on myocardial strain in children with acute kidney injury receiving continuous kidney replacement therapy: a pilot study.Pediatr Nephrol | Other paper | 2021 |
| A facile synthesis of isotope labeled acylcarnitines.J Labelled Comp Radiopharm | Other paper | 2021 |
| Dietary l-carnitine Supplementation Modifies the Lipopolysaccharide-Induced Acute Phase Reaction in Dairy Cows.Animals (Basel) | Other paper | 2021 |
| L-carnitine suppresses cisplatin-induced renal injury in rats: impact on cytoskeleton proteins expression.Toxicol Res (Camb) | Other paper | 2021 |
| [Possibilities of sequential levocarnitin and acetylcarnitin treatment in correcting cognitive deficiency in patients with cardiovascular diseases].Zh Nevrol Psikhiatr Im S S Korsakova | Other paper | 2021 |
| OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo.Drug Deliv | Other paper | 2020 |
| Glutaric acidemia type 1: Treatment and outcome of 168 patients over three decades.Mol Genet Metab | Other paper | 2020 |
| Effect of levocarnitine administration in patients with chronic liver disease.Exp Ther Med | Other paper | 2020 |
| L-Carnitine Mitigates Oxidative Stress and Disorganization of Cytoskeleton Intermediate Filaments in Cisplatin-Induced Hepato-Renal Toxicity in Rats.Front Pharmacol | Other paper | 2020 |
| Effect of L-carnitine on the expression of the apoptotic genes Bcl-2 and Bax.Clin Exp Reprod Med | Other paper | 2020 |
| Efficacy of L-carnitine and propranolol in the management of acute theophylline toxicity.Toxicol Res (Camb) | Other paper | 2020 |
| Electromembrane Extraction of Highly Polar Compounds: Analysis of Cardiovascular Biomarkers in Plasma.Metabolites | Other paper | 2019 |
| Effects of Co-Administration of Bone Marrow Stromal Cells and L-Carnitine on The Recovery of Damaged Ovaries by Performing Chemotherapy Model in Rat.Int J Fertil Steril | Other paper | 2019 |