# Ipamorelin

NNC 26-0161

https://graded.pl/en/substances/ipamorelin · Checked: Not yet

Preliminary version. The editors have not finished checking this card, and grades may change.

A peptide that raises growth hormone. Not approved in the EU or US.

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## Short answers

### Does ipamorelin work?

A peptide that raises growth hormone. Not approved in the EU or US. Muscle mass: grade E, not clear. Nobody measured muscle. Rats grew longer bones and gained weight, and in ferrets on chemotherapy it reduced weight loss. There are no studies of muscle in people.

### Is Ipamorelin legal?

PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). US: No approval. The FDA drug register has no such medicine.

### Is ipamorelin banned in sport?

Banned in sport, WADA 2026.

### Is Ipamorelin safe?

Little data. An early study after bowel surgery and little else. A 2026 review says very little is known about the safety of peptides like this one in people.

## What studies show

| | | | |
|---|---|---|---|
| Muscle mass | E | Not clear | Nobody measured muscle. Rats grew longer bones and gained weight, and in ferrets on chemotherapy it reduced weight loss. There are no studies of muscle in people. |

## Studies we have read

- The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism. (Physiol Behav 2024; In animals) https://pubmed.ncbi.nlm.nih.gov/39043357/
- Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. (Growth Horm IGF Res 1999; In animals) https://pubmed.ncbi.nlm.nih.gov/10373343/

## Is it legal

- PL: No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. https://www.ema.europa.eu/en/documents/other/article-57-product-data_en.xlsx (Checked: Not yet)
- EU: No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). https://www.ema.europa.eu/en/documents/other/article-57-product-data_en.xlsx (Checked: Not yet)
- US: No approval. The FDA drug register has no such medicine. https://www.accessdata.fda.gov/scripts/cder/daf/ (Checked: Not yet)

## Doping

Banned in sport, WADA 2026. https://zoek.officielebekendmakingen.nl/trb-2026-25.html

## How much research exists

- Scientific papers: 51
- Studies with random groups: 2
- Registered studies in people: 3
- These are search results. A count shows how much exists, not how good the studies are. 1 Nov 2026.

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Open data: CC BY 4.0, https://creativecommons.org/licenses/by/4.0/
