CJC-1295 vs Sermorelin
Side by side: what studies show, whether it is legal, doping and risks. No winner is shown on purpose.
| CJC-1295 | Sermorelin | |
|---|---|---|
| Type | A synthetic substance that raises growth hormone. Sold with or without DAC, an add-on that makes it last longer. | A fragment of the hormone that tells the body to release growth hormone. It was sold in the US as Geref, which has since been withdrawn. |
| Stage | Work stopped | Work stopped |
| Is it legal (PL) | No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. | No approval. The European medicines database (EMA) lists no such medicine in Poland (9 October 2026). The Polish register was down, so we could not check it directly. |
| Is it legal (EU) | No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). | No approval. The European medicines database (EMA), which covers EU and national approvals, lists no such medicine (9 October 2026). |
| Is it legal (US) | No approval. The FDA drug register has no such medicine. | No approval. The FDA register marks Geref as withdrawn. |
| Doping | Banned in sport, WADA 2026 | Banned in sport, WADA 2026 |
| Safety | Little data | Little data |
| Risk of fakes | Medium | Medium |
| Muscle mass | C Not clear. In studies with random groups in healthy adults, it raised growth hormone and IGF-1, a hormone made in response to it, for several days. Nobody measured muscle or strength. | D Conflicting results. One small study of 19 people aged 55 to 71, without random groups: everyone got placebo first, then the drug. Body mass without fat rose in men but not in women. No study tested people who train. |